Evidence map›Paper›PMID 37910246›Full record

GuidelineSurgical endoscopy2023

EAES Multidisciplinary Rapid Guideline: systematic review, meta-analysis, GRADE assessment and evidence-informed recommendations on the surgical management of paraesophageal hernias.

Sheraz R Markar, Nainika Menon, Nadia Guidozzi, Katerina-Maria Kontouli, Dimitrios Mavridis, Alexandros Andreou, Felix Berlth, Luigi Bonavina, Alfred Cushieri, Lana Fourie and 11 more

Open access · greenAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Gastropexy may reduce symptomatic recurrence in paraesophageal hernia repair: a Scandinavian retrospective multicenter study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Observational
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 10 countries.

Sheraz R MarkarDepartment of General Surgery, Oxford University Hospitals, Oxford, UK.
Nainika MenonNuffield Department of Surgery, University of Oxford, Oxford, UK.
Nadia GuidozziDepartment of General Surgery, University of Witwatersrand, Johannesburg, South Africa.
Katerina-Maria KontouliDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Dimitrios MavridisDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Alexandros AndreouDepartment of Surgery, York Teaching Hospital NHS Foundation Trust, York, UK.
Felix BerlthDepartment of General, Visceral and Transplant Surgery, University Medical Center, Mainz, Germany.
Luigi BonavinaDivision of General and Foregut Surgery, Department of Biomedical Sciences for Health, IRCCS Policlinico San Donato, University of Milan, Milan, Italy.
Alfred CushieriInstitute for Medical Science and Technology, University of Dundee, Dundee, Scotland, UK.
Lana FourieDepartment of Visceral Surgery, Clarunis, University Centre for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.
James GossageDepartment of General Surgery, Guy's and St Thomas' NHS Trust, London, SE1 7EH, UK.
Caroline GronnierEsophagogastric Surgery Unit, Haut Lévêque Hospital, Centre Hospitalier Universitaire Bordeaux, University of Bordeaux, Bordeaux, France.
Eric J HazebroekDepartment of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
Sheila KrishnadathDepartment of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium.
Donald E LowDepartment of Thoracic Surgery and Thoracic Oncology, Virginia Mason Medical Center Seattle, Seattle, USA.
Mimi McCordHeartburn Cancer UK, Basingstoke, UK.
Roos E PouwDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Location Vrije Universiteit, Amsterdam, The Netherlands.
David I WatsonFlinders Medical Centre, Oesophagogastric Surgery Unit, Bedford Park, SA, Australia.
Francesco Maria CarranoDepartment of General Surgery, Busto Arsizio Circolo Hospital ASST-Valle Olona, Busto Arsizio, Italy.
Monica OrtenziDepartment of General Surgery, Università Politecnica Delle Marche, Ancona, Italy.
Stavros A AntoniouDepartment of Surgery, Papageorgiou General Hospital, Thessaloníki, Greece. stavros.antoniou@hotmail.com.ORCID 0000-0002-4630-6748
University of Ioannina · GRUniversity of Oxford · GBAmsterdam University Medical Centers · NLErasmus MC · NLFlinders University · AUJohannes Gutenberg University Mainz · DEKing's College London · GBMarche Polytechnic University · ITOspedale di Circolo di Busto Arsizio · ITPapageorgiou General Hospital · GRRijnstate Hospital · NLUniversité de Bordeaux · FRUniversity of Dundee · GBUniversity of Milan · ITUniversity of the Witwatersrand · ZAVirginia Mason Medical Center · USYork Teaching Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew evidence has emerged since latest guidelines on the management of paraesophageal hernia, and guideline development methodology has evolved. Members of the European Association for Endoscopic Surgery have prioritized the management of paraesophageal hernia to be addressed by pertinent recommendations.

objectiveTo develop evidence-informed clinical practice recommendations on paraesophageal hernias, through evidence synthesis and a structured evidence-to-decision framework by an interdisciplinary panel of stakeholders.

methodsWe performed three systematic reviews, and we summarized and appraised the certainty of the evidence using the GRADE methodology. A panel of general and upper gastrointestinal surgeons, gastroenterologists and a patient advocate discussed the evidence in the context of benefits and harms, the certainty of the evidence, acceptability, feasibility, equity, cost and use of resources, moderated by a Guidelines International Network-certified master guideline developer and chair. We developed the recommendations in a consensus meeting, followed by a modified Delphi survey.

resultsThe panel suggests surgery over conservative management for asymptomatic/minimally symptomatic paraesophageal hernias (conditional recommendation), and recommends conservative management over surgery for asymptomatic/minimally symptomatic paraesophageal hernias in frail patients (strong recommendation). Further, the panel suggests mesh over sutures for hiatal closure in paraesophageal hernia repair, fundoplication over gastropexy in elective paraesophageal hernia repair, and gastropexy over fundoplication in patients who have cardiopulmonary instability and require emergency paraesophageal hernia repair (conditional recommendation). A strong recommendation means that the proposed course of action is appropriate for the vast majority of patients. A conditional recommendation means that most patients would opt for the proposed course of action, and joint decision-making of the surgeon and the patient is required. Accompanying evidence summaries and evidence-to-decision frameworks should be read when using the recommendations. This guideline applies to adult patients with moderate to large paraesophageal hernias type II to IV with at least 50% of the stomach herniated to the thoracic cavity. The full guideline with user-friendly decision aids is available in https://app.magicapp.org/#/guideline/j7q7Gn .

conclusionAn interdisciplinary panel provides recommendations on key topics on the management of paraesophageal hernias using highest methodological standards and following a transparent process. GUIDELINE REGISTRATION NUMBER: PREPARE-2023CN018.

Indexed as

Hernia, HiatalLaparoscopyAdultFundoplicationGRADE ApproachHumansMeta-Analysis as TopicStomachSystematic Reviews as TopicDiaphragmatic herniaGuidelinesHiatal herniaMeshParaesophageal hernia

Identifiers

PMID37910246
OpenAlexW4388141942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.