Evidence map›Paper›PMID 37909439›Full record

ArticleCardiovascular & hematological agents in medicinal chemistry2024

Comparison between the ECG Outcomes of Metoprolol and Bisoprolol.

Ahmad Abdulrahman Almeman, Yousef Obaid Alharbi, Abdulaziz Sulaiman Alwahhabi, Abdulaziz Abdullah Almutairi, Moayad Yousef Alnasr, Abdulrahaman Almesnid

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Cardiovascular & hematological agents in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ahmad Abdulrahman AlmemanDepartment of Pharmacology, College of Medicine, Prince Sultan Cardiac Center, Qassim University, Buraydah, Qassim, Saudi Arabia.
Yousef Obaid AlharbiCollege of Medicine, Qassim University, Buraydah, Qassim, Saudi Arabia.
Abdulaziz Sulaiman AlwahhabiDepartment of Pharmacology, College of Medicine, Prince Sultan Cardiac Center, Qassim University, Buraydah, Qassim, Saudi Arabia.
Abdulaziz Abdullah AlmutairiDepartment of Pharmacology, College of Medicine, Prince Sultan Cardiac Center, Qassim University, Buraydah, Qassim, Saudi Arabia.
Moayad Yousef AlnasrDepartment of Pharmacology, College of Medicine, Prince Sultan Cardiac Center, Qassim University, Buraydah, Qassim, Saudi Arabia.
Abdulrahaman AlmesnidDepartment of Pharmacology, College of Medicine, Prince Sultan Cardiac Center, Qassim University, Buraydah, Qassim, Saudi Arabia.
Qassim University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeta-blockers are essential agents in the management of cardiovascular diseases, such as heart failure, acute myocardial infarction (MI), and cardiac arrhythmias. However, there are diurnal variations in the cardioprotective effects of the subgroups as a result of their different pharmacokinetic, pharmacodynamic, and pharmacogenetic profiles.

objectivesWe aimed to compare metoprolol and bisoprolol in terms of electrocardiogram (ECG) outcomes.

methodsA retrospective cross-sectional study was conducted at Prince Sultan Cardiac Center. The trial included 404 patients who met the inclusion criteria (204 in the metoprolol arm and 200 in the bisoprolol arm). Using case record forms that had already been created, information, such as patient demographics, medical histories, and treatment histories, was taken from their medical files. The most recent ECG records were also gathered. The ethical approval for this study was obtained from Qassim ethical committee (approval number: 45-44-902).

resultsThere was no significant difference found between the patients in both arms in terms of baseline characteristics, age, or sex.

conclusionIn this retrospective cross-sectional study, we have compared the effects of metoprolol and bisoprolol beta blockers on ECG changes. The findings have indicated no difference between metoprolol and bisoprolol groups in terms of all ECG readings, particularly PR/ms, QTC-ms, and ventricular rate. Further studies are required to confirm these findings.

Indexed as

BisoprololElectrocardiographyMetoprololAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesBisoprololMetoprololBeta-blockersbisoprololcardiovascular diseasesECGmetoprololpharmacogenetics.

Identifiers

PMID37909439
OpenAlexW4388140201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.