Evidence map›Paper›PMID 37909220›Full record

ArticleCancer medicine2023

Disparities among Black and Hispanic colorectal cancer patients: Findings from the California Cancer Registry.

Joel Sanchez Mendez, Ruoxuan Wang, Lihua Liu, Juanjuan Zhang, Stephanie L Schmit, Jane Figueiredo, Heinz-Josef Lenz, Mariana C Stern

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Racial and Ethnic Disparities in Hepatocellular Carcinoma Treatment Receipt in the United States: A Systematic Review and Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Joel Sanchez MendezDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-5552-1020
Ruoxuan WangDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lihua LiuDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Juanjuan ZhangDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Stephanie L SchmitGenomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Jane FigueiredoDepartment of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars Sinai Medical Center, Los Angeles, California, USA.
Heinz-Josef LenzNorris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Mariana C SternDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-9777-4683
University of Southern California · USCedars-Sinai Medical Center · USCleveland Clinic · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
USC PE-GCS: Optimizing Engagement of Hispanic Colorectal Cancer Patients in Cancer Genomic Characterization StudiesU2CCA252971 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JOHN D. CARPTEN, HEINZ JOSEF LENZ · 2021 to 2026
$19.3M
Tissue Modeling CoreU54CA233465 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Bodour Salhia · 2018 to 2026
$11.9M
Variation in tumor-associated immune profiles and colorectal cancer outcomesR01CA248931 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI SCHMIT, STEPHANIE L. · 2021 to 2025
$3.5M
Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral originsR01CA238087 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI FIGUEIREDO, JANE C., SCHMIT, STEPHANIE L. · 2019 to 2024
$3.2M
CDC HHS 5NU58DP006344NCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015INCI NIH HHS P30 CA014089NCI NIH HHS P30CA014089NCI NIH HHS R01 CA238087NCI NIH HHS R01CA238087NCI NIH HHS R01CA24893NCI NIH HHS R01 CA248931NCI NIH HHS U2C CA252971NCI NIH HHS U2CCA252971NCI NIH HHS U54 CA233465NCI NIH HHS U54CA233465
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is the third most common cancer in California and second among Hispanic/Latinx (H/L) males. Data from the California Cancer Registry were utilized to investigate the differential impact on CRC outcomes from demographic and clinical characteristics among non-Hispanic white (NHW), non-Hispanic Black (NHB), U.S. born (USB), and non-U.S. born (NUSB) H/L patients diagnosed during 1995-2020.

methodsWe identified 248,238 NHW, 28,433 NHB, and 62,747 H/L cases (32,402 NUSB and 30,345 USB). Disparities across groups were evaluated through case frequencies, odds ratios (OR) from logistic regression, and hazard ratios (HR) from Cox regression models. All statistical tests were two-sided.

resultsNHB patients showed a higher proportion of colon tumors (75.8%) than NHW (71.5%), whereas both NUSB (65.9%) and USB (66.9%) H/L cases had less (p < 0.001). In multivariate models, NUSB H/L cases were 15% more likely than NHW to have rectal cancer. Compared to NHW, NHB cases had the greatest proportion of Stage IV diagnoses (26.0%) and were more likely to die of CRC (multivariate HR = 1.12; 95% CI = 1.10-1.15). Instead, NUSB H/L patients were less likely to die of CRC (multivariate HR = 0.87; 95% CI = 0.85-0.89) whereas USB H/L did not differ from NHW.

conclusionsNHB and H/L cases have more adverse characteristics at diagnosis compared to NHW cases, with NHB cases being more likely to die from CRC. However, NUSB H/Ls cases showed better survival than NHW and US born H/L patients. These findings highlight the importance of considering nativity among H/L populations to understand cancer disparities.

Indexed as

Black or African AmericanColorectal NeoplasmsHealth Status DisparitiesHispanic or LatinoCaliforniaHumansMaleRegistriesAfrican Americancolorectal cancerdisparitiesHispanicLatinoregistry

Identifiers

PMID37909220
PMCPMC10709728
OpenAlexW4388112314

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.