Evidence map›Paper›PMID 37909215›Full record

ArticleLab on a chip2023

Versatility and stability optimization of flow-focusing droplet generators

David McIntyre, Ali Lashkaripour, Diana Arguijo, Polly Fordyce, Douglas Densmore

Abstract read
In one paragraph

Article in Lab on a chip, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David McIntyreBiomedical Engineering Department, Boston University, MA, USA. dougd@bu.edu.ORCID http://orcid.org/0000-0003-3508-4139
Ali LashkaripourDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-1734-9634
Diana ArguijoBiomedical Engineering Department, Boston University, MA, USA. dougd@bu.edu.ORCID http://orcid.org/0000-0002-3781-0328
Polly FordyceDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-9505-0638
Douglas DensmoreBiological Design Center, Boston University, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7666-6808

Funding

Leveraging spectral encoding for high dimensional biological multiplexingDP2GM123641 · NIGMS · STANFORD UNIVERSITY · PI FORDYCE, POLLY MORRELL · 2016 to 2016
$2.4M
Synthetic Biology and Biotechnology (SB2) Predoctoral Training ProgramT32GM130546 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CHEN, CHRISTOPHER S, KHALIL, AHMAD SAMIR · 2019 to 2023
$1.0M
NIGMS NIH HHS DP2 GM123641NIGMS NIH HHS T32 GM130546
6 · The paper itself

Abstract

Droplet generation is a fundamental component of droplet microfluidics, compartmentalizing biological or chemical systems within a water-in-oil emulsion. As adoption of droplet microfluidics expands beyond expert labs or integrated devices, quality metrics are needed to contextualize the performance capabilities, improving the reproducibility and efficiency of operation. Here, we present two quality metrics for droplet generation: performance versatility, the operating range of a single device, and stability, the distance of a single operating point from a regime change. Both metrics were characterized

Identifiers

PMID37909215
PMCPMC10694034

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.