Evidence map›Paper›PMID 37908689›Full record

ArticleFrontiers in public health2023

Post-marketing safety surveillance for both CRM197 and TT carrier proteins PCV13 in Jiangsu, China.

Ran Hu, Yuanbao Liu, Lei Zhang, Guodong Kang, Borong Xu, Mingma Li, Jing Yu, Yuanyuan Zhu, Hongxiong Guo, Zhiguo Wang

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ran HuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Yuanbao LiuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Lei ZhangJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Guodong KangJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Borong XuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Mingma LiDepartment of Epidemiology and Health Statistics, Southeast University School of Public Health, Nanjing, China.
Jing YuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Yuanyuan ZhuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Hongxiong GuoJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Zhiguo WangJiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study is to evaluate the safety of two kinds of PCV13 carriers by monitoring the occurrence of adverse event following immunization (AEFI) after the launch of two kinds of PCV13 carriers in Jiangsu Province, China. Methods: The AEFI Information System (CNAEFIS) of mainland China was used to monitor the incidence and classification of adverse reactions of the CRM197-carrier protein PCV13 and TT-carrier protein PCV13 vaccines. Results: There was no statistical difference between the cumulative reported incidence of AEFI between the two vaccines from 2020 to 2022 ( Conclusion: Both vaccines perform well in terms of safety. We did not identify any new/unexpected safety concern from the NAEFISS during a 4 years timespan.

Indexed as

ImmunizationVaccinationBacterial ProteinsCarrier ProteinsBacterial ProteinsCarrier ProteinsCRM197 (non-toxic variant of diphtheria toxin)adverse reactioncarrier proteinpneumococcal polysaccharide conjugate vaccinepost-marketing surveillancesafetyvaccine

Identifiers

PMID37908689
PMCPMC10613985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.