Evidence map›Paper›PMID 37908669›Full record

ReviewInternational journal of nanomedicine2023

Manganese-Based Nanotheranostics for Magnetic Resonance Imaging-Mediated Precise Cancer Management.

Ruochen Du, Ziwei Zhao, Jing Cui, Yanan Li

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Manganese-Templated Nontrivial Structures for MRI and Therapy.Journal of the American Chemical Society · 2026
    Article
  3. Article
  4. Monitoring Pharmacological Treatment of Breast Cancer with MRI.Current issues in molecular biology · 2025
    Review
  5. Review
  6. Review
  7. Multifunctional BiInternational journal of pharmaceutics: X · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ruochen DuDepartment of Laboratory Animal Center, Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Ziwei Zhao *College of Medical Imaging, Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Jing Cui *College of Public Health, Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Yanan LiCollege of Medical Imaging, Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manganese (Mn)-based magnetic resonance imaging (MRI) has become a competitive imaging modality for cancer diagnosis due to its advantages of non-invasiveness, high resolution and excellent biocompatibility. In recent years, a variety of Mn contrast agents based on different material systems have been synthesized, and a series of multi-purpose Mn nanocomposites have also emerged, showing satisfactory relaxation efficiency and MRI performance thus possess the transformation and application value in MRI-synergized cancer diagnosis and treatment. This tutorial review starts from the classification and properties of Mn-based nanomaterials, and then summarizes various preparation and functionalization strategies of nanosized Mn contrast agents, especially focuses on the latest progress of Mn contrast agents in MRI-synergized precise cancer theranostics. In addition, present review also discusses the current clinical transformation obstacles such as unclear molecular mechanisms, potential nanotoxicity, and scale production constraints. This paper provides evidence-based recommendations about the future prospects of multifunctional nanoplatforms, as well as technical guidance and panoramic expectations for the design of clinically meaningful cancer management programs.

Indexed as

ManganeseNeoplasmsContrast MediaHumansMagnetic Resonance ImagingTheranostic NanomedicineContrast MediaManganesemagnetic resonance imagingmalignant tumormanganeseprecise diagnosistargeted therapy

Identifiers

PMID37908669
PMCPMC10614655
OpenAlexW4388141374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.