ArticleJCEM case reports2023
Hyperthyroidism Due to Graves Disease After Radiofrequency Ablation.
Article in JCEM case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Case series of de novo occurrence of Graves' disease following thermal ablation for benign thyroid nodules: an uncommon event that should be considered.European thyroid journal · 2025Article
- The evolving therapeutic landscape of Graves' disease in adults: present and future.European thyroid journal · 2025Review
- Thyrotoxicosis due to Hashimoto's disease triggered by radiofrequency ablation for low-risk papillary thyroid microcarcinoma: A case report.Radiology case reports · 2025Article
- Graves' disease diagnosed nearly six months after microwave ablation of benign thyroid nodules: a case report.BMC endocrine disorders · 2025Article
- Hyperthyroidism after radiofrequency ablation for thyroid nodule.The Kaohsiung journal of medical sciences · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Management options for benign, autonomously functioning, and malignant thyroid nodules were limited to surgery or targeting by radioactive iodine before the availability of radiofrequency ablation (RFA). Despite being a relatively new technique, RFA may be favored for patients of high surgical risk, and for those who wish to avoid hypothyroidism. Although insurance coverage for the procedure can be a significant barrier, several groups of investigators have shown improved quality of life for RFA compared to surgery, due to the less invasive nature and favorable risk profile. Hyperthyroidism due to transient thyroiditis is a known risk of RFA, secondary to direct trauma and subsequent thyroid hormone release. Here we present a case of an adult with large, symptomatic, multinodular goiter, with no prior history of thyroid autoimmunity, who underwent RFA with successful volume reduction of two nodules, but who developed acute hyperthyroidism due to Graves disease eight weeks after RFA. Larger studies evaluating the risks of RFA should evaluate for incident hyperthyroidism, specifically for Graves disease/thyroid autoimmunity, as this could represent an additional risk of the procedure.
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Registered trials
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