SynthesisJournal of obesity2023
White Matter Integrity Abnormalities in Healthy Overweight Individuals Revealed by Whole Brain Meta-Analysis of Diffusion Tensor Imaging Studies.
Synthesis in Journal of obesity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Disruptions of white matter in adolescents with internet game disorder: evidence from seed-based d mapping.Brain imaging and behavior · 2025Pooled it
- An Investigation of the Correlation Between Total Intracranial Volume and Body Mass Index.Saudi medical journal · 2026Article
- Understanding Cognitive Decline in Aging: Mechanisms and Mitigation Strategies - A Narrative Review.Clinical interventions in aging · 2025Review
- Novel brain biomarkers of obesity in young adult women based on statistical measurements of white matter tracts.PloS one · 2025Article
- Relationships between abdominal adipose tissue and neuroinflammation with diffusion basis spectrum imaging in midlife obesity.Obesity (Silver Spring, Md.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to conduct a coordinate-based meta-analysis (CBMA) to investigate white matter (WM) abnormalities in healthy individuals with overweight or obesity. Methods: A systematic literature search using Web of Science and PubMed datasets was performed. Original investigations that used diffusion tensor imaging (DTI) to explore fractional anisotropy (FA) differences between healthy overweight/obese individuals and normal weight controls were collected. The meta-analysis was conducted using the seed-based Results: The analysis included five studies comprising 232 overweight/obese individuals and 219 healthy normal weight controls. The findings showed that overweight/obese individuals exhibited reduced fractional anisotropy (FA) in specific regions, namely, the right superior longitudinal fasciculus (SLF), the splenium of the corpus callosum (CC), and the right median network, cingulum. Meta-regression analysis further revealed that these FA reductions were associated with age. Conclusion: These findings provided insights into the potential impact of overweight/obesity on cognition, emotion, and neural functions and highlighted the significance of early prevention and intervention for overweight on the basis of neuroimaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.