Evidence map›Paper›PMID 37908363›Full record

ArticleFrontiers in immunology2023

Oral exposure to

Jin Yuan, Ping Tong, Xuanyi Meng, Yong Wu, Xin Li, Jinyan Gao, Hongbing Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Mouse Models of Food Allergies: Where Do They Take Us?Clinical reviews in allergy & immunology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin YuanState Key Laboratory of Food Science and Resource, Nanchang University, Nanchang, China.
Ping TongState Key Laboratory of Food Science and Resource, Nanchang University, Nanchang, China.
Xuanyi MengSino-German Joint Research Institute, Nanchang University, Nanchang, China.
Yong WuSino-German Joint Research Institute, Nanchang University, Nanchang, China.
Xin LiState Key Laboratory of Food Science and Resource, Nanchang University, Nanchang, China.
Jinyan GaoCollege of Food Science & Technology, Nanchang University, Nanchang, China.
Hongbing ChenState Key Laboratory of Food Science and Resource, Nanchang University, Nanchang, China.
State Key Laboratory of Food Science and Technology · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recent work highlighted the importance of environmental contaminants in the development of allergic diseases. Methods: The intestinal mucosal barrier, Th (helper T) cells, DCs (dendritic cells), and intestinal flora were analyzed with flow cytometry, RNA-seq, and 16s sequencing in the present study to demonstrate whether the exposure of enterotoxins like Results and discussion: We found that co-exposure to SEB and Ovalbumin (OVA) could impair the intestinal barrier, imbalance the intestinal Th immune, and cause the decline of intestinal flora diversity in OVA-sensitized mice. Moreover, with the co-stimulation of SEB, the transport of OVA was enhanced in the Caco-2 cell monolayer, the uptake and presentation of OVA were promoted in the bone marrow dendritic cells (BMDCs), and Th cell differentiation was also enhanced. In summary, co-exposure to SEB in allergens should be considered a food allergy risk factor.

Indexed as

Food HypersensitivityStaphylococcus aureusAnimalsCaco-2 CellsEnterotoxinsHumansMiceOvalbuminT-Lymphocytes, Helper-InducerEnterotoxinsOvalbumindendritic cellsfood allergygut microbiotaStaphylococcus aureus enterotoxin BT cells

Identifiers

PMID37908363
PMCPMC10615071
OpenAlexW4387674192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.