Evidence map›Paper›PMID 37908354›Full record

ArticleFrontiers in immunology2023

Schistosomiasis-associated pulmonary hypertension unveils disrupted murine gut-lung microbiome and reduced endoprotective Caveolin-1/BMPR2 expression.

Ygor Marinho, Elizabeth S Villarreal, Sammy Y Aboagye, David L Williams, Jun Sun, Claudia L M Silva, Sarah E Lutz, Suellen D Oliveira

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Endothelial c-IAP2 loss amplifies P2X7 receptor-driven inflammation and worsens schistosomiasis-associated pulmonary hypertension.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
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  8. Mechanisms of lung endothelial cell injury and survival in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  9. Altered purinergic P2X7 and ABiomedical journal · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. P2YFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Ygor MarinhoVascular Immunobiology Lab, Department of Anesthesiology, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
Elizabeth S VillarrealVascular Immunobiology Lab, Department of Anesthesiology, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
Sammy Y AboagyeDepartment of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States.
David L WilliamsDepartment of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States.
Jun SunDepartment of Medicine, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
Claudia L M SilvaMolecular and Biochemical Pharmacology Lab, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Sarah E LutzDepartment of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
Suellen D OliveiraVascular Immunobiology Lab, Department of Anesthesiology, College of Medicine, University of Illinois Chicago, Chicago, IL, United States.
University of Illinois Chicago · USRush University Medical Center · USIllinois College · USUniversidade Federal do Rio de Janeiro · BRUniversity of Illinois Urbana-Champaign · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK134343 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2023 to 2026
$3.0M
Generation of Endothelial Cell Memory in Inflammatory Vascular DiseaseK01HL159037 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOS SANTOS OLIVEIRA, SUELLEN D'ARC · 2021 to 2025
$800k
NHLBI NIH HHS K01 HL159037NIDDK NIH HHS R01 DK114126NIDDK NIH HHS R01 DK134343
6 · The paper itself

Abstract

Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic

Indexed as

Gastrointestinal MicrobiomeHypertension, PulmonaryPulmonary Arterial HypertensionSchistosomiasisAnimalsBone Morphogenetic Protein Receptors, Type IICaveolin 1Endothelial CellsLungMicePulmonary ArteryBmpr2 protein, mouseBone Morphogenetic Protein Receptors, Type IICav1 protein, mouseCaveolin 1apoptosisBMPR2Cav-1endothelial cellgut microbiomelung microbiomePAHschistosomiasis

Identifiers

PMID37908354
PMCPMC10613683
OpenAlexW4387671402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.