Evidence map›Paper›PMID 37908334›Full record

ArticleFrontiers in physiology2023

Gastrointestinal cell injury and perceived symptoms after running the Boston Marathon.

Melani R Kelly, Dawn M Emerson, Brendon P McDermott, Whitley C Atkins, Cory L Butts, R Mark Laursen, Christopher Troyanos, Andrew Duckett, Jacob Siedlik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Biomarkers of organ stress and injury following the Boston Marathon.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Melani R KellyDepartment of Health, Sport, and Exercise Sciences, University of Kansas, Lawrence, KS, United States.
Dawn M EmersonDepartment of Health, Sport, and Exercise Sciences, University of Kansas, Lawrence, KS, United States.
Brendon P McDermottDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, United States.
Whitley C AtkinsDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, United States.
Cory L ButtsDepartment of Exercise and Nutrition Sciences, Weber State University, Ogden, UT, United States.
R Mark LaursenSargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA, United States.
Christopher TroyanosBoston Athletic Association, Boston, MA, United States.
Andrew DuckettDepartment of Athletics, Boston University, Boston, MA, United States.
Jacob SiedlikDepartment of Exercise Science and Pre-Health Professions, Creighton University, Omaha, NE, United States.
Boston University · USUniversity of Arkansas at Fayetteville · USCreighton University · USUniversity of Kansas · USUtah Valley University · USWeber State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal (GI) disturbances are a prevalent cause of marathon related complaints, and in extreme cases can promote life-threatening conditions such as exertional heat stroke. Our aim was to study intestinal cell injury [via intestinal fatty acid binding protein (I-FABP)] and perceived GI distress symptoms among marathon runners. We also examined potential risk factors (e.g., inadequate sleep) that could exacerbate GI disturbances in healthy, trained endurance runners. This was a parallel mixed-methods study design. 2019 Boston Marathon participants were recruited via email and subjects completed surveys before the race describing demographics and training history. Participants completed a GI questionnaire to assess presence and severity of symptoms, a survey regarding risk factors (e.g., recent illness, medications) that could promote GI disturbances, and provided a urine sample at three time points (immediately pre-race, post-race, and 24-h post-race). Due to weather, blood samples were only collected immediately and 24-h post-race. A total of 40 runners (males:

Indexed as

endurance exercisehydrationintestinal epitheliumintestinal fatty acid binding proteinrace medicine

Identifiers

PMID37908334
PMCPMC10615131
OpenAlexW4387673962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.