Evidence map›Paper›PMID 37908293›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2023

Poor correlation of 2D shear wave elastography and transient elastography in Fontan-associated liver disease: A head-to-head comparison.

Madeleine Gill, Sanjivan Mudaliar, David Prince, Nwe Ni Than, Rachel Cordina, Avik Majumdar

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Unifying FALD assessment-A call to arms.Hepatology communications · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Madeleine GillAustralian National Liver Transplant Unit Royal Prince Alfred Hospital Sydney New South Wales Australia.ORCID https://orcid.org/0000-0002-4201-0173
Sanjivan MudaliarAustralian National Liver Transplant Unit Royal Prince Alfred Hospital Sydney New South Wales Australia.ORCID https://orcid.org/0000-0001-9505-1924
David PrinceAustralian National Liver Transplant Unit Royal Prince Alfred Hospital Sydney New South Wales Australia.ORCID https://orcid.org/0000-0001-8087-0548
Nwe Ni ThanDepartment of Gastroenterology and Hepatology University Hospital Coventry Coventry UK.
Rachel CordinaFaculty of Medicine and Health The University of Sydney Sydney New South Wales Australia.
Avik MajumdarFaculty of Medicine and Health The University of Sydney Sydney New South Wales Australia.ORCID https://orcid.org/0000-0003-2975-4327
The University of Sydney · AURoyal Prince Alfred Hospital · AUUniversity Hospital Coventry · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Fontan-associated liver disease (FALD) is a long-term complication of the Fontan procedure. Guidelines recommend elastography, but the utility of transient elastography (TE) and two-dimensional shear wave elastography (2D SWE) is unknown. We aimed to evaluate the relationship between TE and 2D SWE in FALD. Methods: This prospective cohort study included 25 patients managed in a specialist clinic between January 2018 and August 2021. Trained clinicians performed 2D SWE (GE Logiq-E9) and TE (FibroScan 503 Touch) on the same day under the same conditions. Laboratory, echocardiography, and imaging data were collected. The atrioventricular systolic-to-diastolic duration (AVV S/D ratio) was calculated as a measure of cardiac diastolic function. Results: We analyzed 40 paired measurements. Median age was 22 years. Median liver stiffness measurement (LSM) was 15.4 kPa (12.1-19.6) by TE and 8.0 kPa (7.0-10.3) ( Conclusions: In FALD, TE and 2D SWE are poorly correlated. LSM by either modality was not associated with known risk factors for liver fibrosis or Fontan function. Based on these data, the role of elastography in FALD is uncertain.

Indexed as

cirrhosisechocardiographyelastographyfibrosisFontanliver stiffness

Identifiers

PMID37908293
PMCPMC10615175
OpenAlexW4386738403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.