Evidence map›Paper›PMID 37908220›Full record

ArticleJCEM case reports2023

Type B Insulin Resistance Syndrome: A Rare Cause of Hypoglycemia.

Salman Zahoor Bhat, Sooyoung Lim, Aniket Sidhaye, Amir H Hamrahian

Erratum issuedOpen access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Severe Insulin Resistance Syndromes: Clinical Spectrum and Management.International journal of molecular sciences · 2025
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Salman Zahoor BhatDivision of Endocrinology, Diabetes and Metabolism, John Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0000-0003-0304-4044
Sooyoung LimDivision of Endocrinology, Diabetes and Metabolism, John Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Aniket SidhayeDivision of Endocrinology and Metabolism, John Hopkins School of Medicine, Baltimore, MD 21287, USA.
Amir H HamrahianDivision of Endocrinology and Metabolism, John Hopkins School of Medicine, Baltimore, MD 21287, USA.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of a Black female patient with a history of type 2 diabetes mellitus and systemic lupus erythematosus, who had a subacute onset of severe hypoglycemia that persisted after cessation of insulin therapy. Biochemical testing revealed hyperinsulinemic hypoglycemia, normal serum triglycerides, and high-normal serum adiponectin levels. Abdominal imaging demonstrated an 11-mm cystic pancreatic lesion. Her clinical history and biochemical test results raised suspicion for type B insulin resistance syndrome (TBIRS), which was confirmed on anti-insulin receptor antibody testing. The patient's hypoglycemia was managed with dietary modification therapy and continuous glucose monitoring. The severity and frequency of hypoglycemic episodes decreased spontaneously. We describe TBIRS and its uncommon hypoglycemic presentation, analyze factors that put TBIRS among the differential diagnosis, and discuss the treatment of TBIRS-associated hypoglycemia.

Indexed as

anti-insulin receptor antibodyautoimmune hypoglycemiadiabetes mellituspancreatic cysttype B insulin resistance syndrome

Identifiers

PMID37908220
PMCPMC10580449
OpenAlexW4386700152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.