Evidence map›Paper›PMID 37908218›Full record

ArticleJCEM case reports2023

Metastatic Merkel Cell Carcinoma Within a Cortisol-producing Adrenal Adenoma.

Lauren Cutrone, Jose Subauste, Celso Gomez-Sanchez, Sarah Joiner

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lauren CutroneDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Jose SubausteDepartment of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA.
Celso Gomez-SanchezDepartment of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA.
Sarah JoinerDepartment of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA.ORCID https://orcid.org/0000-0002-1467-9961
G.V. (Sonny) Montgomery VA Medical Center · USUniversity of Mississippi Medical Center · US

Funding

Adrenal cell ATP1A1 mutations and mechanisms of aldosterone biosynthesisR01HL144847 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2019 to 2022
$1.3M
BLRD VA I01 BX004681NHLBI NIH HHS R01 HL144847
6 · The paper itself

Abstract

A 54-year-old man with hypertension, type 2 diabetes mellitus, and a history of Merkel cell carcinoma (MCC) of the right thigh presented to the emergency department with a 4-day history of right lower-quadrant abdominal pain associated with constipation and decreased appetite. Workup showed a heterogenous 6-cm right adrenal mass with macroscopic fat. Imaging was suggestive of benign pathology. Hormonal workup for the adrenal nodule led to the diagnosis of Cushing syndrome. The patient underwent a right adrenalectomy for Cushing syndrome with pathology revealing a 6.5-cm adrenocortical adenoma harboring a 2-cm, well-circumscribed neuroendocrine tumor consistent with metastatic MCC. Adrenal collision tumors are exceedingly rare. This case describes a collision tumor that has not previously been identified-a cortisol-producing adrenal adenoma and metastatic MCC.

Indexed as

adrenal collision tumorCushing syndromeMerkel cell carcinoma

Identifiers

PMID37908218
PMCPMC10580440
OpenAlexW4386955234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.