ArticleJournal of extracellular vesicles2023
Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ.
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In one paragraph
Article in Journal of extracellular vesicles, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- A Dual-Mode In Situ EV-miRNA Profiling Platform for Machine-Learning-Assisted Gastric Cancer Liquid Biopsy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Light-induced extracellular vesicle and particle adsorption.Nature methods · 2025Article
- A light-induced micropatterning technique for extracellular vesicles and particles.Nature methods · 2025Article
- Amplifying mutational profiling of extracellular vesicle mRNA with SCOPE.Nature biotechnology · 2025Article
- Article
- Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content.Advanced healthcare materials · 2025Article
- Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014-2023).Pharmaceutics · 2024Review
- The new advance of exosome-based liquid biopsy for cancer diagnosis.Journal of nanobiotechnology · 2024Review
- Simultaneous Protein and RNA Analysis in Single Extracellular Vesicles, Including Viruses.ACS nano · 2024Article
- Specific Extracellular Vesicles, Generated and Operating at Synapses, Contribute to Neuronal Effects and Signaling.International journal of molecular sciences · 2024Review
- Emerging advanced approaches for liquid biopsy:Theranostics · 2024Review
- Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ.Journal of extracellular vesicles · 2023Article
- Roles of extracellular vesicles in glioblastoma: foes, friends and informers.Frontiers in oncology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 6 institutions in 1 country.
Jingjing ZhangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Xilal Y RimaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0001-5633-5887
Xinyu WangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Luong T H NguyenWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-1811-6194
Kristin HuntoonDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Yifan MaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Paola Loreto PalacioDepartment of Pediatrics, Division of Neurology, Nationwide Children's Hospital, Columbus, Ohio, USA.
Kim Truc NguyenWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Karunya AlbertWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Minh-Dao Duong-ThiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Nicole WaltersWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Kwang Joo KwakSpot Biosystems Ltd., Palo Alto, California, USA.
Min Jin YoonWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Hong LiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Jacob Doon-RallsWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Colin L HiseyWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Daeyong LeeDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Yifan WangDepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jonghoon HaDepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kelsey ScherlerInstitute for Systems Biology, Seattle, Washington, USA.
Shannon FallenInstitute for Systems Biology, Seattle, Washington, USA.
Inyoul LeeInstitute for Systems Biology, Seattle, Washington, USA.
Andre F PalmerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Wen JiangDepartment of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Setty M MagañaDepartment of Pediatrics, Division of Neurology, Nationwide Children's Hospital, Columbus, Ohio, USA.
Kai WangInstitute for Systems Biology, Seattle, Washington, USA.
Betty Y S KimDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
L James LeeWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.
Eduardo ReáteguiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-8271-8205
The Ohio State University · USInstitute for Systems Biology · USThe University of Texas MD Anderson Cancer Center · USThe University of Texas Southwestern Medical Center · USNationwide Children's Hospital · USPhoton Spot (United States) · US
Funding
Multi-parametric Integrated Molecular Detection of SARS-CoV-2 from Biofluids by Adapting Single Extracellular Vesicle Characterization TechnologiesU18TR003807 · NCATS · OHIO STATE UNIVERSITY · PI LEE, INYOUL, LEE, LY JAMES · 2021 to 2022
$1.8MMicrofluidics Array Based Sorting, Isolation, and RNA Analysis in Single Extracellular V csiclesUH3TR002884 · NCATS · OHIO STATE UNIVERSITY · PI KIM, BETTY, REATEGUI, EDUARDO · 2021 to 2022
$1.7MMicrofluidics Array Based Sorting, Isolation, and RNA Analysis in Single Extracellular V csiclesUG3TR002884 · NCATS · OHIO STATE UNIVERSITY · PI KIM, BETTY, REATEGUI, EDUARDO · 2019 to 2020
$822kNCATS NIH HHS U18 TR003807NCATS NIH HHS U18TR003807NCATS NIH HHS UG3 TR002884NCATS NIH HHS UG3TR002884NCATS NIH HHS UH3 TR002884NCATS NIH HHS UH3TR002884NIH HHS
Abstract
The molecular heterogeneity of extracellular vesicles (EVs) and the co-isolation of physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of EV bulk biomarker characterization. Herein, we present a single-EV and particle (siEVP) protein and RNA assay (
Indexed as
Extracellular VesiclesGlioblastomaMicroRNAsHumansLipopolysaccharidesLipoproteinsRNA, MessengerLipopolysaccharidesLipoproteinsMicroRNAsRNA, Messengerextracellular RNAglioblastoma multiformeheterogeneitymultiparametricsingle extracellular vesiclesingle lipoprotein
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.