Evidence map›Paper›PMID 37908130›Full record

ReviewTechnology in cancer research & treatment

Proton Beam Therapy and Photon-Based Magnetic Resonance Image-Guided Radiation Therapy: The Next Frontiers of Radiation Therapy for Hepatocellular Carcinoma.

Peter Zaki, Michael D Chuong, Stephanie K Schaub, Simon S Lo, Mariam Ibrahim, Smith Apisarnthanarax

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Peter ZakiDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.ORCID 0000-0002-7451-4712
Michael D ChuongDepartment of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.ORCID 0000-0001-8328-7518
Stephanie K SchaubDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.ORCID 0000-0002-5148-379X
Simon S LoDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
Mariam IbrahimSchool of Medicine, St. George's University, St. George's, Grenada.
Smith ApisarnthanaraxDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
University of Washington · USSt. George's University · GD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

External beam radiation therapy (EBRT) has increasingly been utilized in the treatment of hepatocellular carcinoma (HCC) due to technological advances with positive clinical outcomes. Innovations in EBRT include improved image guidance, motion management, treatment planning, and highly conformal techniques such as intensity-modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT). Moreover, proton beam therapy (PBT) and magnetic resonance image-guided radiation therapy (MRgRT) have expanded the capabilities of EBRT. PBT offers the advantage of minimizing low- and moderate-dose radiation to the surrounding normal tissue, thereby preserving uninvolved liver and allowing for dose escalation. MRgRT provides the advantage of improved soft tissue delineation compared to computerized tomography (CT) guidance. Additionally, MRgRT with online adaptive therapy is particularly useful for addressing motion not otherwise managed and reducing high-dose radiation to the normal tissue such as the stomach and bowel. PBT and online adaptive MRgRT are emerging technological advancements in EBRT that may provide a significant clinical benefit for patients with HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsProton TherapyRadiotherapy, Image-GuidedHumansMagnetic Resonance SpectroscopyRadiotherapy Planning, Computer-Assistedadaptive radiotherapyhepatocellular carcinomaliverMR-guided radiation therapyMRIproton beam therapyradiotherapystereotactic ablative radiotherapystereotactic body radiation therapytargeted

Identifiers

PMID37908130
PMCPMC10621304
OpenAlexW4388141310

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.