Evidence map›Paper›PMID 37908015›Full record

ArticleClinical hypertension2023

Prevalence of hypertension among antiretroviral therapy naïve patients in Lagos, Nigeria.

Oluwatosin Odubela, Nkiruka Odunukwe, Nasheeta Peer, Adesola Zaidat Musa, Babatunde Lawal Salako, Andre Pascal Kengne

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Article in Clinical hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Oluwatosin OdubelaDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. odubstosin08@gmail.com.ORCID http://orcid.org/0000-0002-4432-9137
Nkiruka OdunukweClinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Nasheeta PeerDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Adesola Zaidat MusaClinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Babatunde Lawal SalakoClinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Andre Pascal KengneDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Funding

EDCTP TMA2017GSF-1962- CaDERAL
6 · The paper itself

Abstract

backgroundThe gains from successful antiretroviral therapy (ART) roll-out could be compromised by the increasing burden of non-communicable diseases, particularly cardiovascular diseases among people living with HIV (PLWH). Hypertension remains a significant contributor to cardiovascular diseases. This study aims to determine the prevalence and determinants of hypertension among ART-naïve PLWH in a large ART clinic in Lagos, Nigeria. MATERIALS AND

methodsThis study uses data collected from adult ART-naïve PLWH enrolled at an ART clinic over ten years. Participants aged 18 years and older, not pregnant, and not accessing care for post-exposure prophylaxis were included in the study. Hypertension was defined as systolic and diastolic blood pressure greater than or equal to 140 mmHg and 90 mmHg, respectively. Logistic regressions were used to investigate the factors associated with hypertension.

resultsAmong the 10 426 participants included in the study, the majority were females (66%) and aged 25-49 years (84%). The crude prevalence of hypertension was 16.8% (95%CI 16.4 - 17.2) while the age and sex standardised prevalence rate was 21.9% (95%CI 20.7 - 23.2), with males (25.8%, 95%CI 23.5 - 28.0) having a higher burden compared with females (18.3%, 95%CI 17.0 - 19.6). Increasing age, male gender, overweight or obesity, co-morbid diabetes mellitus or renal disease, and CD4 count ≥ 201 cells/μL were significantly associated with prevalent hypertension.

conclusionThere was a substantial burden of hypertension among ART-naïve PLWH, which was associated with the traditional risk factors of the condition. This highlights the need to integrate screening and care of hypertension into routine HIV management for optimal care of PLWH.

Indexed as

ART-naïveHIVHypertensionNigeriaPLWHPrevalence

Identifiers

PMID37908015
PMCPMC10619289

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