Evidence map›Paper›PMID 37908009›Full record

ArticleMaternal health, neonatology and perinatology2023

Maternal and perinatal outcomes of women with vaginal birth after cesarean section compared to repeat cesarean birth in select South Asian and Latin American settings of the global network for women's and children's health research.

Lester Figueroa, Margo Harrison, Manolo Mazariegos, Shivaprasad Goudar, Avinash Kavi, Richard Derman, Archana Patel, Prabir Das, Patricia L Hibberd, Sarah Saleem and 8 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Maternal health, neonatology and perinatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Estimating the prevalence of vaginal birth after cesarean section and repeat cesarean section: An analysis of nationally representative household surveys in 59 low- and middle-income countries.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 6 countries.

Lester FigueroaInstituto de Nutrición de Centroamérica y Panamá -INCAP, Calzada Roosevelt 6-25 zona 11, C.A, Guatemala City, Guatemala. lfigueroa@incap.int.ORCID http://orcid.org/0000-0003-1732-0361
Margo HarrisonUniversity of Colorado School of Medicine, Denver, CO, USA.
Manolo MazariegosInstituto de Nutrición de Centroamérica y Panamá -INCAP, Calzada Roosevelt 6-25 zona 11, C.A, Guatemala City, Guatemala.
Shivaprasad GoudarKLE University's Jawaharlal Nehru Medical College, Belgaum, India.
Avinash KaviKLE University's Jawaharlal Nehru Medical College, Belgaum, India.
Richard DermanThomas Jefferson University, Philadelphia, PA, USA.
Archana PatelLata Medical Research Foundation, Nagpur, India.
Prabir DasLata Medical Research Foundation, Nagpur, India.
Patricia L HibberdBoston University, Boston, MA, USA.
Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Farnaz NaqviDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University School of Medicine, New York, NY, USA.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh.
Sk Masum BillahInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b), Dhaka, Bangladesh.
William A PetriUniversity of Virginia, Charlottesville, VG, USA.
Elizabeth M McClureRTI International, Durham, NC, USA.
Sylvia TanRTI International, Durham, NC, USA.
Nancy F KrebsUniversity of Colorado School of Medicine, Denver, CO, USA.
Aga Khan University · PKInstitute of Nutrition of Central America and Panama · GTJawaharlal Nehru Medical College · INLata Medical Research Foundation · INRTI International · USUniversity of Colorado Denver · USColumbia University · USInternational Centre for Diarrhoeal Disease Research · BDThe University of Sydney · AUThomas Jefferson University · USUniversity of Virginia · US

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
COLORADO WRHR CAREER DEVELOPMENT CENTERK12HD001271 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Saketh R Guntupalli · 1999 to 2026
$8.9M
UAB/AKU Global Network Research UnitU01HD040607 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOLDENBERG, ROBERT L · 2001 to 2012
$8.5M
Complementary feeding: a Global Network cluster randomized controlled trialU01HD040657 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL · 2001 to 2012
$8.1M
UMKC-JNMC Global Network for Women's and Children's Health Research UnitU01HD042372 · NICHD · UNIVERSITY OF MISSOURI KANSAS CITY · PI DERMAN, RICHARD J · 2001 to 2012
$6.9M
Neonatal Resuscitation in Developing CountriesU01HD043464 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2003 to 2012
$6.6M
NIDDK National Research Service Award (NRSA) T32 Diversity Administrative SupplementT32DK007658 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Kristen Elizabeth Boyle, Ihuoma U Eneli · 1991 to 2026
$6.0M
Evidence-Based Global Health Interventions for Mothers and Children, ArgentinaU01HD040477 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI BUEKENS, PIERRE · 2001 to 2013
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
University of Virginia - icddr,b Research Unit for Women's and Children's Health ResearchUG1HD096730 · NICHD · UNIVERSITY OF VIRGINIA · PI Christian A Chisholm · 2018 to 2026
$5.3M
Safe Pregnancy by Infectious Disease Control in KinshasaU01HD043475 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOSE, CARL · 2003 to 2008
$5.2M
NICHD NIH HHS K12 HD001271NICHD NIH HHS U01 HD040477NICHD NIH HHS U01 HD040574NICHD NIH HHS U01 HD040607NICHD NIH HHS U01 HD040636NICHD NIH HHS U01 HD040657NICHD NIH HHS U01 HD042372NICHD NIH HHS U01 HD043464NICHD NIH HHS U01 HD043475NICHD NIH HHS U10 HD076474NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078439NICHD NIH HHS UG1 HD096730NIDDK NIH HHS T32 DK007658
6 · The paper itself

Abstract

objectiveOur objective was to analyze a prospective population-based registry including five sites in four low- and middle-income countries to observe characteristics associated with vaginal birth after cesarean versus repeat cesarean birth, as well as maternal and newborn outcomes associated with the mode of birth among women with a history of prior cesarean. HYPOTHESIS: Maternal and perinatal outcomes among vaginal birth after cesarean section will be similar to those among recurrent cesarean birth.

methodsA prospective population-based study, including home and facility births among women enrolled from 2017 to 2020, was performed in communities in Guatemala, India (Belagavi and Nagpur), Pakistan, and Bangladesh. Women were enrolled during pregnancy, and delivery outcome data were collected within 42 days after birth.

resultsWe analyzed 8267 women with a history of prior cesarean birth; 1389 (16.8%) experienced vaginal birth after cesarean, and 6878 (83.2%) delivered by a repeat cesarean birth. Having a repeat cesarean birth was negatively associated with a need for curettage (ARR 0.12 [0.06, 0.25]) but was positively associated with having a blood transfusion (ARR 3.74 [2.48, 5.63]). Having a repeat cesarean birth was negatively associated with stillbirth (ARR 0.24 [0.15, 0.49]) and, breast-feeding within an hour of birth (ARR 0.39 [0.30, 0.50]), but positively associated with use of antibiotics (ARR 1.51 [1.20, 1.91]).

conclusionsIn select South Asian and Latin American low- and middle-income sites, women with a history of prior cesarean birth were 5 times more likely to deliver by cesarean birth in the hospital setting. Those who delivered vaginally had less complicated pregnancy and labor courses compared to those who delivered by repeat cesarean birth, but they had an increased risk of stillbirth. More large scale studies are needed in Low Income Country settings to give stronger recommendations.

trial registrationNCT01073475, Registered February 21, 2010, https://clinicaltrials.gov/ct2/show/record/NCT01073475 .

Indexed as

Breastfeeding initiationCesarean birthFacility-based deliveryLow- and middle-income countriesMaternal outcomesMode of birthNeonatal outcomesRepeat cesarean birthVaginal birth after cesarean

Identifiers

PMID37908009
PMCPMC10619270
OpenAlexW4388069632

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.