Evidence map›Paper›PMID 37907960›Full record

ArticleBMC research notes2023

High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study.

Sulaiman Lakoh, Le Yi, James B W Russell, Juling Zhang, Stephen Sevalie, Yongkun Zhao, Joseph Sam Kanu, Peng Liu, Sarah K Conteh, Christine Ellen Elleanor Williams and 10 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 9 countries.

Sulaiman Lakoh *College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone. lakoh2009@gmail.com.
Le Yi *Tropical Infectious Disease Prevention and Control Center, Freetown, Sierra Leone.
James B W RussellCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Juling ZhangDepartment of Clinical Laboratory, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China.
Stephen SevalieCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Yongkun ZhaoTropical Infectious Disease Prevention and Control Center, Freetown, Sierra Leone.
Joseph Sam KanuCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Peng LiuDepartment of Emergency Medicine, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China.
Sarah K ContehMinistry of Health and Sanitation, Government of Sierra Leone, Freetown, Sierra Leone.
Christine Ellen Elleanor WilliamsCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Umu BarrieInfectious Disease Research Network, Freetown, Sierra Leone.
Olukemi AdekanmbiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Darlinda F JibaMinistry of Health and Sanitation, Government of Sierra Leone, Freetown, Sierra Leone.
Matilda N KamaraCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Daniel SesayMinistry of Health and Sanitation, Government of Sierra Leone, Freetown, Sierra Leone.
Gibrilla F DeenCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Joseph Chukwudi OkeibunorWorld Health Organization Regional Office for Africa, Brazzaville, Congo.
George A YendewaDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Xuejun GuoTropical Infectious Disease Prevention and Control Center, Freetown, Sierra Leone. xuejung@yahoo.com.
Emmanuel FirimaClinical Research Unit, Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.
University of Sierra Leone · SLMinistry of Health and Sanitation · SLSierra Leone Urban Research Centre · SLChinese PLA General Hospital · CNJohns Hopkins University · USLesotho Planned Parenthood Association · LSMinistry of Health · BBUniversity College Hospital, Ibadan · NGWorld Health Organization Regional Office for Africa · CG

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveCatheter-associated urinary tract infections (CAUTI) are common worldwide, but due to limited resources, its actual burden in low-income countries is unknown. Currently, there are gaps in knowledge about CAUTI due to lack of surveillance activities in Sierra Leone. In this prospective cohort study, we aimed to determine the incidence of CAUTI and associated antibiotic resistance in two tertiary hospitals in different regions of Sierra Leone.

resultsThe mean age of the 459 recruited patients was 48.8 years. The majority were females (236, 51.3%). Amongst the 196 (42.6%) catheterized patients, 29 (14.8%) developed CAUTI. Bacterial growth was reported in 32 (84%) patients. Escherichia coli (14, 23.7%), Klebsiella pneumoniae (10, 17.0%), and Klebsiella oxytoca (8, 13.6%) were the most common isolates. Most isolates were ESBL-producing Enterobacteriaceae (33, 56%) and WHO Priority 1 (Critical) pathogens (38, 71%). Resistance of K. pneumoniae, K. oxytoca, E. coli, and Proteus mirabilis was higher with the third-generation cephalosporins and penicillins but lower with carbapenems, piperacillin-tazobactam and amikacin. To reduce the high incidence of CAUTI and multi-drug resistance organisms, urgent action is needed to strengthen the microbiology diagnostic services and develop and implement catheter bundles that provide clear guidance for catheter insertion, care and removal.

Indexed as

Escherichia coliUrinary Tract InfectionsAnti-Bacterial Agentsbeta-LactamasesCathetersDrug Resistance, MicrobialFemaleHospitalsHumansIncidenceKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedProspective StudiesSierra LeoneAnti-Bacterial Agentsbeta-LactamasesCarbapenem resistance Enterobacteriaceae (CRE)Catheter-associated urinary tract Infections (CAUTI)Extended spectrum β-lactamase (ESBL)-producing EnterobacteriaceaeMultidrug resistance organisms (MRO)WHO priority pathogens

Identifiers

PMID37907960
PMCPMC10619308
OpenAlexW4388076106

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.