Evidence map›Paper›PMID 37907946›Full record

ReviewCritical care (London, England)2023

Redefining ARDS: a paradigm shift.

Jesús Villar, Tamas Szakmany, Giacomo Grasselli, Luigi Camporota

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07328997 (Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07328997 completednot on this mapstarted 2024, after this paper: background citation

Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence

TypeobservationalSponsorShanghai Zhongshan HospitalRan2024 to 2025Enrolled400ConditionsARDS (Acute Respiratory Distress Syndrome), AI (Artificial Intelligence)ArmsCT scan
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Ventilator-Induced Lung Liquid and Alveolar Rupture.Journal of clinical medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Jesús VillarCIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, 28029, Madrid, Spain. jesus.villar54@gmail.com.
Tamas SzakmanyDepartment of Intensive Care Medicine & Anesthesia, Aneurin Bevan University Health Board, Newport, NP20 2UB, Wales, UK.
Giacomo GrasselliDepartment of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Luigi CamporotaDepartment of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Aneurin Bevan University Health Board · GBKing's College London · GBSt. Michael's Hospital · CAUniversity of Milan · IT

Funding

ERAPerMed JTC_2021Fundación Canaria Instituto de Investigación Sanitaria de Canarias PIFIISC20-51, PIFIISC21-36Instituto de Salud Carlos III CB06/06/1088, PI19/00141, AC21_2/00039Ministero della Salute Current Research IRCCS
6 · The paper itself

Abstract

Although the defining elements of "acute respiratory distress syndrome" (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate whether ARDS is a discrete nosological entity. After almost 60 years, it is appropriate to examine how critical care has modeled this fascinating syndrome and affected patient's outcome. Given that the diagnostic criteria of ARDS (e.g., increased pulmonary vascular permeability and diffuse alveolar damage) are difficult to ascertain in clinical practice, we believe that a step forward would be to standardize the assessment of pulmonary and extrapulmonary involvement in ARDS to ensure that each patient can receive the most appropriate and effective treatment. The selection of treatments based on arbitrary ranges of PaO

Indexed as

Respiratory Distress SyndromeCritical CareHumansLungTreatment OutcomeAcute hypoxemic respiratory failureAcute respiratory distress syndromeClinical trialsDefinitionsMechanical ventilationPrognosisStandardizationStratification

Identifiers

PMID37907946
PMCPMC10619227
OpenAlexW4388070406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.