ArticleBMC psychiatry2023
Quality of life and its predictors in first-episode schizophrenia and individuals at clinical high-risk for psychosis.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Quality of life in individuals at clinical high risk for psychosis: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2026Pooled it
- Comorbid Mood and Anxiety Disorder Diagnoses in Patients With First-Episode Psychosis: Comparison Between Research and Clinical Diagnoses.Early intervention in psychiatry · 2026Article
- Quality of Life in Adolescents with Schizophrenia: The Importance of Social Cognition and Residual Psychopathology in the Context of CYP2D6 Polymorphism.Healthcare (Basel, Switzerland) · 2026Article
- Independent Contributions of Social Functioning Deficits and Internalized Stigma to Quality of Life in Clinically Stable Patients with Schizophrenia: A Hierarchical Regression Analysis.Psychology research and behavior management · 2026Article
- The intervention targets of family functioning and cognitive insight in community-dwelling individuals with schizophrenia: a simulated network analysis.Frontiers in psychiatry · 2026Article
- The Moderating Role of Social Functioning in the Relationship Between Stigma and Quality of Life in Rural Chinese Patients with Schizophrenia: A Cross-Sectional Study.Neuropsychiatric disease and treatment · 2026Article
- Exploration of the associations between violent and aggressive behaviors risk and NHHR, TyG in patients with schizophrenia: an SHAP interpretable machine learning prediction and FAERS pharmacovigilance analysis.Lipids in health and disease · 2025Article
- Association between social support and quality of life in community-dwelling schizophrenics: the mediating roles of anxiety and depression symptoms.Health and quality of life outcomes · 2025Article
- The prevalence and clinical correlates of severe anxiety symptoms in first-episode drug-naïve schizophrenia: a Chinese population study.BMC psychiatry · 2025Article
- [Association between stigma and quality of life in community-dwelling patients with schizophrenia: Multiple mediating roles of anxiety and depression symptoms].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Exploring the interplay of psychiatric symptoms, antipsychotic medications, side effects, employment status, and quality of life in Chronic Schizophrenia.BMC psychiatry · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis is a cross-sectional study comparing the degree of subjective quality of life (QOL) impairment and its predictive factors in first-episode schizophrenia (FES) and individuals at clinical high-risk (CHR) for psychosis.
methodsSeventy-seven FES, 59 CHR, and 64 healthy controls (HC) were included. The QOL of all participants was assessed using the World Health Organization Quality of Life (WHOQOL)-Brief Form (BREF). Psychiatric symptoms of individuals with FES were assessed with the Positive and Negative Syndrome Scale (PANSS), five factors were further identified through factor analysis; for individuals with CHR and HC, the Scale of Prodromal Symptoms (SOPS) was used.
resultsThe total and four sub-domain scores of the WHOQOL-BREF in the FES and CHR groups were lower than those of the HC group. The overall and psychological health scores in the CHR group were lowest. In the FES group, after applying Bonferroni's correction, there is a negative correlation between the total QOL scores and anxiety/depressive symptom scores (r = -0.34, P = 0.003). The stepwise multiple regression analysis showed that the QOL of both FES and CHR group were negatively affected by anxiety/depressive symptoms and unemployment (P < 0.05).
conclusionsCompared with FES, CHR individuals are more dissatisfied with their QOL. Although diagnostic assessment of FES and CHR relies heavily on positive symptoms, the QOL is more affected by anxiety/depressive symptoms and social functioning.
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