Evidence map›Paper›PMID 37907639›Full record

ArticleScientific reports2023

Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications.

Korawinwich Boonpisuttinant, Thanachai Taka, Warintorn Ruksiriwanich, Romchat Chutoprapat, Sarinporn Udompong, Rattiya Kansawang, Jinapa Sangsee, Wirinda Chompoo, Kitrawi Samothai, Ratakorn Srisuttee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Polyphenol-Rich Extracts fromAntioxidants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Protective Effects ofInternational journal of molecular sciences · 2026
    Article
  6. Therapeutic potential ofRSC advances · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Korawinwich BoonpisuttinantInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Thanachai TakaiCell Research Institute Laboratory Unit, Bangkok, 10230, Thailand.
Warintorn RuksiriwanichDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand.
Romchat ChutoprapatDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Sarinporn UdompongInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Rattiya KansawangInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Jinapa SangseeInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Wirinda ChompooInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Kitrawi SamothaiInnovative Natural Products from Thai Wisdom Research Unit, Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathumthani, 12130, Thailand.
Ratakorn SrisutteeFaculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok, 10520, Thailand. ratakorn.sr@kmitl.ac.th.
Rajamangala University of Technology · THChulalongkorn University · THKing Mongkut's Institute of Technology Ladkrabang · THMaejo University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant Indian Gooseberry (GIG) or Phyllanthus indofischeri Bennet are commercially cultivated and commonly used herbs in Traditional medicine, especially in Thailand. The aim of this study was to assess the potential of the GIG extracts in anti-aging activities to be a dermatological application. The juice, meat residues, and seeds of GIG collected from Sra Kaeo Province, Thailand, were extracted by the Boiling method (B) and the Maceration process (M) by using 95% ethanol as a solvent. The GIG extracts gave the total phenolic, total flavonoid contents and quercetin contents, as well as exhibited anti-oxidative activities. The GIG-R-B extract inhibited tyrosinase activity and had the highest anti-melanogenesis activity on B

Indexed as

PhyllanthusSkin AgingAntioxidantsHumansMonophenol MonooxygenasePlant ExtractsSkinAntioxidantsMonophenol MonooxygenasePlant Extracts

Identifiers

PMID37907639
PMCPMC10618208
OpenAlexW4388047385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.