Evidence map›Paper›PMID 37907616›Full record

ArticleScientific reports2023

Transcriptome analysis of Corvus splendens reveals a repertoire of antimicrobial peptides.

Shalini Kannoth, Nemat Ali, Ganesh K Prasanth, Kumar Arvind, Mohamed Mohany, Preety Sweta Hembrom, Shemmy Sadanandan, Deepa Azhchath Vasu, Tony Grace

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Shalini KannothDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India.
Nemat AliDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Ganesh K PrasanthDepartment of Biochemistry and Molecular Biology, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India.
Kumar ArvindNeurogenetics Branch, National Institute of Neurological Disorder and Stroke, National Institute of Health, Bethesda, MD, 20892, USA.
Mohamed MohanyDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Preety Sweta HembromDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India.
Shemmy SadanandanDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India.
Deepa Azhchath VasuDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India.
Tony GraceDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India. tonygrace@cukerala.ac.in.
Central University of Kerala · INKing Saud University · SANational Institute of Neurological Disorders and Stroke · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance has become a global health problem associated with high morbidity and mortality. Antimicrobial peptides have been acknowledged as potential leads for prospective anti-infectives. Owing to their scavenging lifestyle, Corvus splendens is thought to have developed robust immunity to pathogens found in their diet, implying that they have evolved mechanisms to resist infection. In the current study, the transcriptome of C. splendens was sequenced, and de novo assembled to identify the presence of antimicrobial peptide genes. 72.09 million high-quality clean reads were obtained which were then de novo assembled into 3,43,503 transcripts and 74,958 unigenes. About 37,559 unigenes were successfully annotated using SwissProt, Pfam, GO, and KEGG databases. A search against APD3, CAMP

Indexed as

Anti-Infective AgentsCrowsAnimalsAntimicrobial PeptidesCathelicidinsEscherichia coliGene Expression ProfilingHumansLipopolysaccharidesStaphylococcus aureusTranscriptomeAnti-Infective AgentsAntimicrobial PeptidesCathelicidinsLipopolysaccharides

Identifiers

PMID37907616
PMCPMC10618271
OpenAlexW4388042925

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.