Evidence map›Paper›PMID 37907557›Full record

ArticleJournal of human genetics2024

Diversity of thought: public perceptions of genetic testing across ethnic groups in the UK.

Benjamin H L Harris, Caitlin McCabe, Hana Shafique, Simon Lammy, Laura Tookman, James Flanagan, Sofia Miron-Barroso, Mark Lythgoe, James Clark, Jason L Walsh and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of human genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Benjamin H L HarrisDepartment of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.ORCID http://orcid.org/0000-0002-8154-8953
Caitlin McCabeSt Anne's College, 56 Woodstock Rd, Oxford, OX2 6HS, UK.
Hana ShafiqueDuke University School of Medicine, Durham, NC, 27710, USA.
Simon LammyDepartment of Neurosurgery, Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, G51 4TF, UK.
Laura TookmanHammersmith Hospital, Imperial College Healthcare NHS trust, London, W12 0HS, UK.
James FlanaganDepartment of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0HS, UK.
Sofia Miron-BarrosoDepartment of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0HS, UK.
Mark LythgoeDepartment of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0HS, UK.
James ClarkDepartment of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0HS, UK.
Jason L WalshHammersmith Hospital, Imperial College Healthcare NHS trust, London, W12 0HS, UK.
Matteo Di GiovannantonioDepartment of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
Jonathan KrellDepartment of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0HS, UK. j.krell@imperial.ac.uk.
Imperial College London · GBImperial College Healthcare NHS Trust · GBUniversity of Oxford · GBDuke University · USQueen Elizabeth University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic testing is becoming rapidly more accessible to the general populous either through or outside healthcare systems. Few large-scale studies have been carried out to gauge public opinion in this growing area. Here, we undertook the largest cross-sectional study on genetic testing in the UK. The primary purpose of this study is to identify the differences in attitudes toward genetic testing across ethnic groups. A cohort of 6500 individuals from a diverse population completed a 72-item survey in a cross-sectional study. Responses between ethnic minority and white individuals in the UK were compared using a wilcoxon rank-sum and chi-square tests. The white cohort was approximately twice as likely to have taken a genetic test and 13% more had heard about genetic testing before the survey. The ethnic minority cohort appeared more apprehensive about the impact of genetic testing on employability. This study highlights that in the UK, significant differences in opinions regarding genetic testing exist between white individuals and ethnic minority individuals. There is an urgent need to develop more inclusive strategies to equally inform individuals from all backgrounds to avoid disparities in the utilisation of genetic testing.

Indexed as

EthnicityPublic OpinionCross-Sectional StudiesGenetic TestingHumansMinority GroupsUnited Kingdom

Identifiers

PMID37907557
PMCPMC10774120
OpenAlexW4388138855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.