Evidence map›Paper›PMID 37907387›Full record

Trial reportEuropean urology oncology2024

Effect of a Home-based Walking Intervention on Cardiopulmonary Fitness and Quality of Life Among Men with Prostate Cancer on Active Surveillance: The Active Surveillance Exercise Randomized Controlled Trial.

Erin L Van Blarigan, Stacey A Kenfield, Adam Olshen, Neil Panchal, Katriel Encabo, Imelda Tenggara, Rebecca E Graff, Alexander S Bang, Katsuto Shinohara, Matthew R Cooperberg and 5 more

2 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European urology oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 6 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02435472 nacompletednot on this map

A Randomized Clinical Trial of Exercise vs. Usual Care Among Men Opting for Active Surveillance for Prostate Cancer

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2024Enrolled104ConditionsLocalized Prostate Cancer, Active Surveillance for Prostate CancerArmsExercise, Cardiopulmonary Exercise Test (CPET)
NCT06451120 phase2recruitingnot on this map

Study of Platelet Rich Plasma (PRP) Injections With Symptomatic Knee Osteoarthritis for Biomarker Exploration in Young and Old Human Subjects

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2027Enrolled60ConditionsOsteoarthritis, Articular Cartilage, Musculoskeletal DisordersArmsPlatelet-Rich Plasma (PRP) Injections, Centrifuge, Control saline injection
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 6 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  6. Physical activity and pain in people with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Erin L Van BlariganDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Stacey A KenfieldDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Adam OlshenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Neil PanchalDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA.
Katriel EncaboDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Imelda TenggaraDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Rebecca E GraffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Alexander S BangDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.
Katsuto ShinoharaDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Matthew R CooperbergDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Peter R CarrollDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Lee W JonesMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Kerri Winters-StoneOregon Health & Sciences University Knight Cancer Institute, Portland, OR, USA.
Anthony LukeDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA.
June M ChanDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. Electronic address: june.chan@ucsf.edu.
University of California, San Francisco · USUCSF Helen Diller Family Comprehensive Cancer Center · USMemorial Sloan Kettering Cancer Center · USOregon Health & Science University · US

Funding

Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alan Ashworth · 1999 to 2026
$209.7M
Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Effect of Aerobic Exercise on Genomic Signatures of Prostate Cancer PrognosisR01CA181802 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JUNE ML · 2014 to 2019
$3.1M
NCATS NIH HHS UL1 TR001872NCI NIH HHS P30 CA082103NCI NIH HHS R01 CA181802
6 · The paper itself

Abstract

backgroundActive surveillance (AS) is standard care for most men with low-risk prostate cancer (PC); yet, many men on AS eventually undergo curative therapy. Interventions to lower the risk of cancer progression and fear of recurrence among men on AS for PC are needed.

objectiveTo determine the effect of aerobic exercise on cardiorespiratory fitness, body size, and quality of life (QOL) among men on AS for PC. DESIGN, SETTING, AND

participantsWe conducted a 1:1 randomized controlled trial among 51 men with low-risk PC who elected AS. Participants were enrolled at the University of California, San Francisco.

interventionThe 16-wk intervention included a home-based walking program with a nonlinear exercise prescription tailored to baseline fitness level, heart rate monitor, and weekly phone call with an exercise physiologist. Controls received printed materials. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Cardiorespiratory fitness was measured using VO RESULTS AND LIMITATIONS: Between 2016 and 2021, we randomized 51 men to intervention (n = 26) or control (n = 25). Follow-up was 88% (45/51), 85% (22/26) in the intervention and 92% (23/25) in the control group. At 16 wk, the intervention group had a higher mean VO

conclusionsA home-based walking program improved VO PATIENT SUMMARY: Moderate to vigorous aerobic exercise improves fitness and quality of life among men on active surveillance for prostate cancer.

Indexed as

Cardiorespiratory FitnessProstatic NeoplasmsQuality of LifeWalkingAgedExercise TherapyHome Care ServicesHumansMaleMiddle AgedWatchful WaitingActive surveillanceCardiorespiratory fitnessExerciseFear of cancer recurrenceProstate cancer

Identifiers

PMID37907387
PMCPMC12535774
OpenAlexW4388005828

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.