ArticleAnnals of rehabilitation medicine2023
Improved Muscle Mass and Function With Protein Supplementation in Older Adults With Sarcopenia: A Meta-Analysis.
Article in Annals of rehabilitation medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Effects of supplemental protein in older people: an overview of meta-analyses.Age and ageing · 2025Pooled it
- Sarcopenia interventions targeted at improving muscle health in adults with cancer: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Protein-enriched soup and weekly exercise improve muscle health: A randomized trial in mid-to-old age with inadequate protein intake.Journal of cachexia, sarcopenia and muscle · 2024Trial
- Sarcopenia: From Global Consensus to Korean Implementation - A Narrative Review and Standpoint.Annals of geriatric medicine and research · 2026Review
- Lumbar paraspinal muscle quality and disability in older adults: insights from the SarcoSpine cohort.BMC geriatrics · 2026Observational
- Planetary health diet index and low muscle mass in adults aged 20-60 years: exploratory evaluation of a dairy-upweighted outcome-specific adaptation.Frontiers in nutrition · 2026Article
- Clinically Meaningful or Just Measurable? What Physiologic Outcomes Tell Us About Aging Interventions.Current geriatrics reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective: To systematically review the effects of protein supplementation in older adults with sarcopenia.
methods: A systematic literature search was conducted in PubMed, Cochrane Library, and Embase databases until May 2023. The inclusion criteria were as follows: (1) randomized controlled trials with a quantitative study design; (2) studies with a study group of older adults with sarcopenia; (3) studies comparing muscle mass, muscle strength, and performance of older adults with sarcopenia after protein supplementation; and (4) studies published up to May 2023.
results: Six retrospective comparative studies, including 715 patients, met the inclusion criteria. The nutritional supplementation group exhibited significant improvement in appendicular skeletal muscle mass (standardized mean difference [SMD]=0.41; 95% confidence interval [CI], 0.24-0.58; p<0.001; I
conclusion: Nutritional supplementation with protein increased appendicular muscle mass in older adults with sarcopenia and improved handgrip strength and SPPB scores.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.