Evidence map›Paper›PMID 37906840›Full record

ReviewAnnual review of animal biosciences2024

Sperm in the Mammalian Female Reproductive Tract: Surfing Through the Tract to Try to Beat the Odds.

David J Miller

Abstract readReview
In one paragraph

Review in Annual review of animal biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. From reservoir to rendezvous: the journey of sperm through the oviduct.Reproduction, fertility, and development · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Effects of genotypes on sperm quality and fertility of buffalo bulls.Journal of advanced veterinary and animal research · 2025
    Article
  10. Review
  11. Review
  12. The Known and Unknown About Female Reproductive Tract Mucus Rheological Properties.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  13. Electrical wave generation and spatial organization in uterine tissue.Journal of the Royal Society, Interface · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David J MillerDepartment of Animal Sciences and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA; email: djmille@illinois.edu.

Funding

Accumulation, Storage, and Release of Sperm in the OviductR01HD095841 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAVID Joel MILLER · 2018 to 2026
$2.5M
NICHD NIH HHS R01 HD095841
6 · The paper itself

Abstract

Mammalian sperm are deposited in the vagina or the cervix/uterus at coitus or at artificial insemination, and the fertilizing sperm move through the female reproductive tract to the ampulla of the oviduct, the site of fertilization. But the destination of most sperm is not the oviduct. Most sperm are carried by retrograde fluid flow to the vagina, are phagocytosed, and/or do not pass barriers on the pathway to the oviduct. The sperm that reach the site of fertilization are the exceptions and winners of one of the most stringent selection processes in nature. This review discusses the challenges sperm encounter and how the few sperm that reach the site of fertilization overcome them. The sperm that reach the goal must navigate viscoelastic fluid, swim vigorously and cooperatively along the walls of the female tract, avoid the innate immune system, and respond to potential cues to direct their movement.

Indexed as

SemenSpermatozoaAnimalsFemaleFertilizationGenitalia, FemaleMaleMammalscervixfertilizationoviductspermuterusviscosity

Identifiers

PMID37906840
PMCPMC11149062

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.