Evidence map›Paper›PMID 37906631›Full record

ArticleClinical immunology communications2023

Disseminated tuberculosis, CMV viraemia & haemophagocytic-lymphohistiocystosis syndrome in an adult patient with anti- IFNγ autoantibodies - case report and brief review.

G I Butel-Simoes, C Kiss, K Kong, L B Rosen, L M Hosking, S Barnes, G A Jenkin, S Megaloudis, B Kumar, S M Holland and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical immunology communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

G I Butel-SimoesMonash Infectious Diseases, Monash Health, Victoria, Australia.
C KissMonash Infectious Diseases, Monash Health, Victoria, Australia.
K KongMonash Infectious Diseases, Monash Health, Victoria, Australia.
L B RosenImmunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, United States.
L M HoskingDepartment of Allergy and Immunology, Royal Children's Hospital, Parkville, Victoria, Australia.
S BarnesMonash Lung Sleep Allergy Immunology, Monash Health, Victoria, Australia.
G A JenkinMonash Infectious Diseases, Monash Health, Victoria, Australia.
S MegaloudisHaematology Laboratory, Monash Pathology, Monash Health, Victoria, Australia.
B KumarAnatomical Pathology Laboratory, Monash Pathology, Monash Health, Victoria, Australia.
S M HollandImmunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, United States.
S OjaimiMonash Infectious Diseases, Monash Health, Victoria, Australia.
Monash Health · AUNational Institute of Allergy and Infectious Diseases · USRoyal Children's Hospital · AU

Funding

Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

We report a case of an adult female with disseminated tuberculosis, cytomegalovirus viraemia and haemophagocytic-lymphohistiocystosis syndrome associated with neutralizing anti- interferon gamma (IFNγ) autoantibodies demonstrated by absent IFNγ stimulated STAT1 phosphorylation in the presence of patient sera. A brief review of immunodeficiency caused by anti-IFNγ autoantibodies is also described.

Indexed as

Anti-interferon gamma autoantibodiesHaemophagocytic lymphohistiocytosisTuberculosis

Identifiers

PMID37906631
PMCPMC10600947
OpenAlexW4386314686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.