Evidence map›Paper›PMID 37906299›Full record

ArticleInternational journal of colorectal disease2023

Comparing continent ileostomy (CI) conversion to repair/redo IPAA: favorable outcomes.

Nils Karl Josef Ecker, Christian Dinh, Gabriela Möslein, Karl-Wilhelm Ecker

Open access · hybridAbstract read
In one paragraph

Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Nils Karl Josef Ecker, Forstmeisterweg 65, D-23568, Lübeck, Germany.ORCID http://orcid.org/0000-0002-0663-7825
Christian Dinh, Iburger Straße 116, D-49082, Osnabrück, Germany.
Gabriela MösleinCenter for Hereditary Tumors, Ev. Krankenhaus BETHESDA, University of Düsseldorf, Heerstraße 219, D-47053, Duisburg, Germany.ORCID http://orcid.org/0000-0002-0639-8350
Karl-Wilhelm EckerDept. of General, Vascular, and Pediatric Surgery, University of Saarland, Homburg, Saar, Germany. karl-wilhelm.ecker@gmx.de.ORCID http://orcid.org/0000-0002-9672-2504
Eckernforde Tanga University · TZEvangelisches Krankenhaus Bethesda · DEOsnabrück University · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to compare the outcomes of repair/redo ileal pouch-anal anastomosis (repair/redo-IPAA) with the conversion of IPAA to continent ileostomy (CI) in an effort to prevent the need for a permanent ileostomy (IS) following IPAA failure.

methodsThis research involved a retrospective analysis of surgical records, employing descriptive statistics and Kaplan-Meier survival analysis.

resultsAmong 57 patients with an IPAA, up to three revisions were necessary due to complications or complete failure. Ultimately, repair/redo-IPAA preserved the IPAA in 14 patients (24.6%), conversion to CI salvaged the pouch in 21 patients (36.8%), and IS was unavoidable in 22 patients (38.6%). The cumulative probability of requiring conversion surgery was calculated to be 54.0% at 20 years, thereby reducing the cumulative risk of IS to 32.3%. The 20-year cumulative probability of pouch salvage by repair/redo IPAA was only 21.9%. However, this rate increased to 67.7% when conversion procedures were considered. Following repair/redo-IPAA, only 8.3% of patients reported evacuation frequencies of ≤ 4 during the day, and 16.7% were evacuation-free at night. In contrast, after conversion to CI, 98.0% of patients reported a maximum of four evacuations in a 24-h period. After undergoing repair/redo IPAA, between half and two-thirds of patients reported experiencing incontinence or soiling, while complete continence was achieved in all patients following conversion to CI. Notably, the majority of patients expressed overall satisfaction with their respective procedures. A positive correlation was identified between very high subjective satisfaction and positive objective surgical outcomes exclusively in patients who underwent conversion to CI.

conclusionWhen complications or failure of IPAA occur, conversion to CI emerges as a highly viable alternative to repair/redo IPAA. This conclusion is supported by the observation that patient satisfaction appears to be closely tied to stable surgical outcomes. To reinforce these findings, further prospective studies are warranted.

Indexed as

Colitis, UlcerativeColonic PouchesProctocolectomy, RestorativeAnastomosis, SurgicalHumansIleostomyPostoperative ComplicationsReoperationRetrospective StudiesContinent ileostomyIleoanal pouchPatient’s satisfactionPouch failurePouch survivalRedo ileoanal pouch

Identifiers

PMID37906299
PMCPMC10618396
OpenAlexW4388042370

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.