Evidence map›Paper›PMID 37905940›Full record

ArticleRenal failure2023

Efficacy of iguratimod on mineral and bone disorders after kidney transplantation: a preliminary study.

Li Sun, Jun Tao, Zhijian Han, Hao Chen, Zhengkai Huang, Zijie Wang, Shuang Fei, Chuanjian Suo, Xiaobing Ju, Ruoyun Tan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Li SunDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jun TaoDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhijian HanDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hao ChenDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhengkai HuangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zijie WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Shuang FeiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chuanjian SuoDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaobing JuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ruoyun TanDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min GuDepartment of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIguratimod has been shown to promote bone formation and inhibit bone resorption in rheumatoid arthritis patients. We aimed to explore its effect on bone metabolism and vascular calcification (VC) in kidney transplant recipients (KTRs).

methodsA

resultsAt 52 weeks after enrollment, the iguratimod group had lower osteocalcin (

conclusionIguratimod is safe, can reduce BTMs and may could attenuate VC in the first year after KT.

Indexed as

Collagen Type IKidney TransplantationBiomarkersBone DensityBone RemodelingCalciumChromonesHumansMineralsOsteocalcinParathyroid HormonePeptidesPhosphorusSulfonamidesBiomarkersCalciumChromonesCollagen Type IiguratimodMineralsOsteocalcinParathyroid HormonePeptidesPhosphorusSulfonamideschronic kidney diseaseiguratimodKidney transplantationmineral and bone disordersvascular calcification

Identifiers

PMID37905940
PMCPMC11001337
OpenAlexW4388033905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.