Evidence map›Paper›PMID 37905908›Full record

ArticlemBio2023

Identification of a DNA-cytosine methyltransferase that impacts global transcription to promote group B streptococcal vaginal colonization.

Haider S Manzer, Tonya Brunetti, Kelly S Doran

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Haider S ManzerDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-2864-6212
Tonya BrunettiDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kelly S DoranDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0003-4232-6837
University of Colorado Anschutz Medical Campus · US

Funding

Host and bacterial mechanisms governing Group B streptococcal persistence in the female genital tractR01AI153332 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2021 to 2025
$2.9M
Modulation of Blood-Brain Barrier Defense and Dysfunction during Bacterial MeningitisR01NS116716 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2020 to 2024
$1.9M
Characterizing the Contribution of the Group B Streptococcal Surface Adhesin BspC Interaction with Host Vimentin to Disease and ColonizationF31AI164674 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MANZER, HAIDER SYED · 2021 to 2022
$69k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F31AI164674-01HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI153332HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS116716NIAID NIH HHS F31 AI164674NIAID NIH HHS R01 AI153332NINDS NIH HHS R01 NS116716
6 · The paper itself

Abstract

importanceGroup B

Indexed as

Streptococcus agalactiaeVaginaBacterial ProteinsDNA-Cytosine MethylasesFemaleGene Expression Regulation, BacterialHumansPregnancyStreptococcal InfectionsTranscription, GeneticBacterial ProteinsDNA-Cytosine MethylasesDcmDNA methylationepigeneticsGroup B Streptococcusmucinvaginal colonization

Identifiers

PMID37905908
PMCPMC10746215
OpenAlexW4388033980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.