Evidence map›Paper›PMID 37905839›Full record

ArticleJournal of virology2023

Microbiota do not restrict rotavirus infection of colon.

Arash Hellysaz, Johan Nordgren, Magdalena Neijd, Magalí Martí, Lennart Svensson, Marie Hagbom

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Arash Hellysaz *Division of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.
Johan Nordgren *Division of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.ORCID 0000-0002-5349-2569
Magdalena NeijdDivision of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.
Magalí MartíDivision of Children's and Women's Health, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.ORCID 0000-0002-1927-4656
Lennart SvenssonDivision of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.
Marie HagbomDivision of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University , Linköping, Sweden.ORCID 0000-0002-9770-4623
Linköping University · SE

Funding

Vetenskapsrådet (VR) 2018-02862Vetenskapsrådet (VR) 2020-06116
6 · The paper itself

Abstract

importanceAlterations of the gut microbiome can have significant effects on gastrointestinal homeostasis leading to various diseases and symptoms. Increased understanding of rotavirus infection in relation to the microbiota can provide better understanding on how microbiota can be used for clinical prevention as well as treatment strategies. Our volumetric 3D imaging data show that antibiotic treatment and its consequent reduction of the microbial load does not alter the extent of rotavirus infection of enterocytes in the small intestine and that restriction factors other than bacteria limit the infection of colonocytes.

Indexed as

ColonGastrointestinal MicrobiomeRotavirus InfectionsAnimalsGastrointestinal TractHumansIntestine, SmallMiceRotaviruscolonenterocytesmicrobiotarotavirus

Identifiers

PMID37905839
PMCPMC10688362
OpenAlexW4388033727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.