Evidence map›Paper›PMID 37905760›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2023

[Clinical effect of different immunosuppressive treatment regimens in children with ocular myasthenia gravis: a retrospective analysis].

Rui-Yan Wang, Hui Chen, Zhi-Xin Huang, Yong Chen, Jian-Min Zhong

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. The role and mechanism of IL‑35 in myasthenia gravis (Review).International journal of molecular medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rui-Yan WangDepartment of Neurology, Jiangxi Children's Hospital, Nanchang 330038, China.
Hui ChenDepartment of Neurology, Jiangxi Children's Hospital, Nanchang 330038, China.
Zhi-Xin HuangDepartment of Neurology, Jiangxi Children's Hospital, Nanchang 330038, China.
Yong ChenDepartment of Neurology, Jiangxi Children's Hospital, Nanchang 330038, China.
Jian-Min ZhongDepartment of Neurology, Jiangxi Children's Hospital, Nanchang 330038, China.
Jiangxi Provincial Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the clinical effect of different immunosuppressive treatment regimens in children with ocular myasthenia gravis (OMG).

methodsA retrospective analysis was conducted on 130 children with OMG who were treated in the Department of Neurology, Jiangxi Children's Hospital, from February 2018 to February 2023. According to the treatment regimen, they were divided into four groups: glucocorticoid (GC) group (

resultsAfter 3 months of treatment, the FK506 group had significantly lower scores of Myasthenia Gravis Quantitative Scale and Myasthenia Gravis-Specific Activities of Daily Living than the other three groups (

conclusionsFor children with OMG, the addition of various immunosuppressants can reduce the dosage of GC and adverse reactions. Among them, FK506 shows superior efficacy compared to other immunosuppressants in the early treatment of OMG.

Indexed as

Myasthenia GravisTacrolimusActivities of Daily LivingChildGlucocorticoidsHumansImmunosuppressive AgentsMycophenolic AcidPrednisoneRetrospective StudiesGlucocorticoidsImmunosuppressive AgentsMycophenolic AcidPrednisoneTacrolimusAdverse reactionChildClinical effectGlucocorticoidImmunosuppressantMyasthenia gravisOcular type

Identifiers

PMID37905760
PMCPMC10621052
OpenAlexW4388034565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.