Evidence map›Paper›PMID 37905738›Full record

Observational studyJournal of the American Geriatrics Society2024

Changes in the burden of medications that may impair driving among older adults before and after a motor vehicle crash.

Melissa R Riester, Adam M D'Amico, Marzan A Khan, Nina R Joyce, Melissa R Pfeiffer, Seth A Margolis, Brian R Ott, Allison E Curry, Thomas A Bayer, Andrew R Zullo

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Melissa R RiesterDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-2196-0134
Adam M D'AmicoCenter for Gerontology and Health Care Research, Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Marzan A KhanCenter for Gerontology and Health Care Research, Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Nina R JoyceDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0001-7611-5494
Melissa R PfeifferCenter for Injury Research and Prevention, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Seth A MargolisDepartment of Neuropsychology, Rhode Island Hospital, Providence, Rhode Island, USA.
Brian R OttDepartment of Neurology, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-4899-7116
Allison E CurryCenter for Injury Research and Prevention, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Thomas A BayerDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-1616-0714
Andrew R ZulloDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-1673-4570
Rhode Island Department of Health · USBrown University · USChildren's Hospital of Philadelphia · US

Funding

Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
The risks and consequences of a motor vehicle crash in older adults with Alzheimer's Disease and Related DementiasR01AG079295 · NIA · BROWN UNIVERSITY · PI JOYCE, NINA · 2022 to 2025
$3.0M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Opioid use in post-acute hip fracture care: prescribing patterns, effectiveness, and safetyR21AG061632 · NIA · BROWN UNIVERSITY · PI BEAUDOIN, FRANCESCA, ZULLO, ANDREW REIS · 2019 to 2020
$462k
NIA NIH HHS R01 AG065722NIA NIH HHS R01AG065722NIA NIH HHS R01 AG077620NIA NIH HHS R01AG077620NIA NIH HHS R01 AG079295NIA NIH HHS R01AG079295NIA NIH HHS R21 AG061632NIA NIH HHS R21AG061632
6 · The paper itself

Abstract

backgroundMedications are one of the most easily modifiable risk factors for motor vehicle crashes (MVCs) among older adults, yet limited information exists on how the use of potentially driver-impairing (PDI) medications changes following an MVC. Therefore, we examined the number and types of PDI medication classes dispensed before and after an MVC.

methodsThis observational study included Medicare fee-for-service beneficiaries aged ≥67 years who were involved in a police-reported MVC in New Jersey as a driver between 2008 and 2017. Analyses were conducted at the "person-crash" level because participants could be involved in more than one MVC. We examined the use of 36 PDI medication classes in the 120 days before and 120 days after MVC. We described the number and prevalence of PDI medication classes in the pre-MVC and post-MVC periods as well as the most common PDI medication classes started and stopped following the MVC.

resultsAmong 124,954 person-crashes, the mean (SD) age was 76.0 (6.5) years, 51.3% were female, and 83.9% were non-Hispanic White. The median (Q

conclusionsA majority of crash-involved older adults were exposed to multiple PDI medications before and after MVC. A greater proportion of person-crashes were associated with an increased rather than decreased number of PDI medications. The reasons why clinicians refrain from stopping PDI medications following an MVC remain to be elucidated.

Indexed as

Accidents, TrafficAutomobile DrivingAgedFemaleHumansMaleMedicareMotor VehiclesNew JerseyRisk FactorsUnited StatesMedicareolder adultspolypharmacyprescription drugstraffic accidents

Identifiers

PMID37905738
PMCPMC10922040
OpenAlexW4388033965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.