Evidence map›Paper›PMID 37905662›Full record

ArticleIn vivo (Athens, Greece)

Clinical Effect of Moisturized Skin Care on Radiation Dermatitis of Head and Neck Cancer.

Pei-Chuan Tsai, Yu-Chang Liu, Tzong Shiun Li, Fei-Ting Hsu, Yuan-Hao Lee, I-Tsang Chiang, Yuan Chang, Chiu-Hsiang Lee

Registry-linked trialAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07357506 (Mitigating Cutaneous Toxicity in Patients Undergoing TomoTherapy; A Randomized Controlled Trial of Skin-Protective Strategies), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07357506 nanot yet recruitingnot on this map

Mitigating Cutaneous Toxicity in Patients Undergoing TomoTherapy; A Randomized Controlled Trial of Skin-Protective Strategies

TypeinterventionalSponsorKing Faisal Specialist Hospital & Research CenterRan2026 to 2028Enrolled104ConditionsHead and Neck CancerArmsFragrance-Free Emollient (Glycerol-Based), A fragrance-free, glycerol-based emollient applied to the skin from day 1 of TomoTherapy., Mepitel Film (Silicone-Based Semi-Permeable Barrier Film)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pei-Chuan Tsai *Center of Hyperbaric Oxygen Center and Wound Care, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.
Yu-Chang Liu *Department of Radiation Oncology, Chang Bing Show Chwan Memorial Hospital, Lukang, Taiwan, R.O.C.
Tzong Shiun LiDepartment of Plastic Surgery, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.
Fei-Ting HsuDepartment of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Yuan-Hao LeeDepartment of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, R.O.C.
I-Tsang ChiangDepartment of Radiation Oncology, Chang Bing Show Chwan Memorial Hospital, Lukang, Taiwan, R.O.C.
Yuan ChangDepartment of Radiology, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan, R.O.C.
Chiu-Hsiang LeeDepartment of Nursing Chung Shan Medical University, Taichung, Taiwan, R.O.C.; csha528@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimRadiation therapy (RT) for head and neck cancer may cause severe radiation dermatitis (RD) resulting in RT interruption and affecting disease control. A few studies address skin moisture changes during RT for head and neck cancer. The purpose of this study was to explore the effect of moisturized skin care (MSC) on severity of RD. PATIENTS AND

methodsThe study includes newly diagnosed head and neck cancer patients undergoing RT. Participants were divided into MSC group and routine skin care (RSC) group based on patient's preferred decision. Skin moisture in the four quadrants of the neck was measured weekly before and after RT. RD was assessed with the Radiation Induced Skin Reaction Assessment Scale (RISRAS) and the Radiation Therapy Oncology Group (RTOG) acute skin toxicity grading criteria.

resultsA total of 54 patients were enrolled, of which 49 patients were suitable for the statistical analysis. There was a statistically significant difference in the RISRAS total score since the 5

conclusionMSC can effectively reduce the severity and delay the onset of RD, while slows down skin moisture decrease during RT.

Indexed as

Head and Neck NeoplasmsRadiodermatitisHumansSkin CaredermatitisMoistureradiation

Identifiers

PMID37905662
PMCPMC10621431

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.