Evidence map›Paper›PMID 37905638›Full record

ArticleIn vivo (Athens, Greece)

The Relationship Between Oxidative Stress, Selenium, and Cumulative Risk in Metabolic Syndrome.

Adrian Marius Danciu, Timea Claudia Ghitea, Alexa Florina Bungau, Cosmin Mihai Vesa

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Observational
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  8. Gut microbiota, nutrients, and depression.Frontiers in nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adrian Marius DanciuDoctoral School of Biological and Biomedical Sciences, University of Oradea, Oradea, Romania.
Timea Claudia GhiteaPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; timea.ghitea@csud.uoradea.ro.
Alexa Florina BungauDoctoral School of Biological and Biomedical Sciences, University of Oradea, Oradea, Romania; pradaalexaflorina@gmail.com.
Cosmin Mihai VesaMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
University of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimOxidative stress in association with metabolic syndrome represents a complex disease entity that has emerged as a significant public health challenge, and it is closely linked to an elevated risk of cardiovascular disease, type 2 diabetes, and even cancer. The objective of this study was to investigate the effectiveness of selenium supplementation in managing oxidative stress while considering a well-balanced diet based on a healthy lifestyle and diet therapy. PATIENTS AND

methodsThe study included a total of 206 participants divided into three groups: the control group consisting of 35 individuals (17.0%) named LC, the diet therapy group comprising 119 individuals (57.8%) named LD, and the diet therapy group supplemented with selenium consisting of 52 individuals (25.2%) named LD+Se. Various clinical parameters such as body mass index (BMI), weight status, fat mass, visceral fat, and sarcopenia index, as well as paraclinical parameters including the HOMA index, cholesterol, triglycerides, C-reactive protein, and HGZ, were evaluated. Additionally, oxidative stress parameters using the FORD, FORT and MIXT tests were measured.

resultsSelenium supplementation, along with FORD and FORT tests, demonstrated effectiveness in individuals with chronic venous disease, with a significantly greater decrease observed in those with chronic venous disease in the LD+Se group.

conclusionPhysiological aging has an important role in triggering or aggravating oxidative stress, and the use of antioxidant products such as selenium can reduce this process.

Indexed as

Diabetes Mellitus, Type 2Metabolic SyndromeSeleniumAntioxidantsHumansOxidative StressAntioxidantsSeleniumFORD testFORT testmetabolic syndromeOxidative stressselenium

Identifiers

PMID37905638
PMCPMC10621440
OpenAlexW4388034881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.