Evidence map›Paper›PMID 37905421›Full record

ArticleCirculation. Cardiovascular quality and outcomes2023

Cost-Effectiveness of AF Screening With 2-Week Patch Monitors: The mSToPS Study.

Matthew R Reynolds, Amy B Stein, Xiaowu Sun, Evangelos Hytopoulos, Steven R Steinhubl, David J Cohen

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02506244 (mHealth Screening to Prevent Strokes), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02506244 nacompletednot on this map

mHealth Screening to Prevent Strokes (mSToPS)

TypeinterventionalSponsorScripps Translational Science InstituteRan2015 to 2020Enrolled6,135ConditionsAtrial FibrillationArmsiRhythm ZIO XT Patch, Wristband by Amiigo
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cost-effectiveness of atrial fibrillation screening programmes across European nations.European heart journal. Quality of care & clinical outcomes · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Matthew R ReynoldsDivision of Cardiology, Lahey Hospital and Medical Center, Burlington, MA (M.R.R.).ORCID 0000-0001-8675-8186
Amy B SteinCVS Health, Woonsocket, RI (A.B.S., X.S.).
Xiaowu SunCVS Health, Woonsocket, RI (A.B.S., X.S.).ORCID 0000-0002-7960-4207
Evangelos HytopoulosiRhythm, San Francisco, CA (E.H.).
Steven R SteinhublScripps Research Translational Institute, La Jolla, CA (S.R.S.).ORCID 0000-0002-9256-7914
David J CohenCardiovascular Research Foundation, New York, NY (D.J.C.).ORCID 0000-0001-9163-724X
CVS Health (United States) · USiRhythm (United States) · USLahey Hospital and Medical Center · USScripps Research Institute · USSt. Francis Hospital · US

Funding

Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
NCATS NIH HHS UL1 TR002550
6 · The paper itself

Abstract

backgroundThe mSToPS study (mHealth Screening to Prevent Strokes) reported screening older Americans at risk for atrial fibrillation (AF) and stroke using 2-week patch monitors was associated with increased rates of AF diagnosis and anticoagulant prescription within 1 year and improved clinical outcomes at 3 years relative to matched controls. Cost-effectiveness of this AF screening approach has not been explored.

methodsWe conducted a US-based health economic analysis of AF screening using patient-level data from mSToPS. Clinical outcomes, resource use, and costs were obtained through 3 years using claims data. Individual costs, survival, and quality-adjusted life years (QALYs) were projected over a lifetime horizon using regression modeling, US life tables, and external data where needed. Adjustment between groups was performed using propensity score bin bootstrapping.

resultsScreening participants (mean age, 74 years, 41% female, median CHA

conclusionsUsing lifetime projections derived from the mSToPS study, we found that AF screening using 2-week patch monitors in older Americans was associated with high economic value. Confirmation of these uncertain findings in a randomized trial is warranted. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02506244.

Indexed as

Atrial FibrillationStrokeAgedAnticoagulantsCost-Benefit AnalysisFemaleHospitalizationHumansMaleQuality-Adjusted Life YearsAnticoagulantsatrial fibrillationcost effectiveness analysiselectrocardiography, ambulatoryoral anticoagulants

Identifiers

PMID37905421
PMCPMC10659247
OpenAlexW4388035398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.