SynthesisEpidemiology and health2023
Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis.
Synthesis in Epidemiology and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies.Addiction (Abingdon, England) · 2026Pooled it
- Pooled it
- Alcohol consumption and its association with cancer, cardiovascular, liver and brain diseases: a systematic review of Mendelian randomization studies.Frontiers in epidemiology · 2024Pooled it
- Randomized, Double-Blind, Placebo-Controlled Trial of Meriva (Curcuminoids) as a Candidate Chemoprevention Agent for Gastric Carcinogenesis.Cancer prevention research (Philadelphia, Pa.) · 2026Trial
- Incidence of Cardiovascular Events and Extrahepatic Malignancies in Steatotic Liver Disease Subgroups.Digestive diseases and sciences · 2026Article
- Lifestyle Behaviors and Physical Health in Canadian Childhood, Adolescent, and Young Adult Cancer Survivors.Cancer medicine · 2026Article
- Prevalence and trends in recent alcohol consumption by cancer history and cancer type in a nationally representative sample of U.S. adults.Cancer causes & control : CCC · 2026Article
- Therapeutic landscape evolution for steatotic liver disease: from lifestyle interventions to precision pharmacotherapy.Clinical and molecular hepatology · 2026Review
- Gastroenterologist's Guide to Assess for Alcohol Use.Digestive diseases and sciences · 2026Review
- Alcohol, Cancer, Neurobiology, and Aviation Safety: Implications for Aerospace Medicine and Pilot Health.Cureus · 2026Review
- Developmental Timing of Alcohol Initiation as a Marker of Adult Clinical Complexity in Alcohol Use Disorder: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Alcohol amount, drinking patterns, and gastric cancer risk: a nationwide study using targeted maximum likelihood estimation.European journal of epidemiology · 2026Article
- Screening older adults for alcohol use in orthopaedic care: Healthcare team perspectives, current practices, and barriers.Journal of orthopaedic reports · 2026Article
- Built and socioeconomic environment: associations with cancer-risk health behaviors among healthy emerging adults.Journal of behavioral medicine · 2026Article
- Hepatitis C virus and extrahepatic malignancies: where we stand and how we can advance the field.Translational cancer research · 2026Article
- Modulation ofInternational journal of molecular sciences · 2026Article
- Assessing the health utility values of patients with six common cancers in China using the QLU-C10D: A cross-sectional survey.iScience · 2026Article
- Early-onset cancer and modifiable risk: quantifying the combined impact of excess body weight and alcohol on breast and colorectal cancer in Italy (18-34 years).BMC public health · 2026Article
- Relative handgrip strength, lifestyles and cancer risk in older adults: a multi-country cohort study.QJM : monthly journal of the Association of Physicians · 2026Article
- The Urgent Need to Address Modifiable Risk Factors to Prevent Young-Onset Colorectal Cancer in Mexico.Cureus · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlcohol consumption is a well-established risk factor for cancer. Despite extensive research into the relationship between alcohol consumption and cancer risk, the effect of light alcohol consumption on cancer risk remains a topic of debate. To contribute to this discourse, we conducted a comprehensive systematic review and meta-analysis.
methodsOur systematic review aimed to investigate the associations between different levels of alcohol consumption and the risk of several cancer types. We focused on analyzing prospective associations using data from 139 cohort studies. Among them, 106 studies were included in the meta-analysis after a quantitative synthesis.
resultsOur analysis did not find a significant association between light alcohol consumption and all-cause cancer risk (relative risk, 1.02; 95% confidence interval, 0.99 to 1.04), but we observed a dose-response relationship. Light alcohol consumption was significantly associated with higher risks of esophageal, colorectal, and breast cancers. Light to moderate drinking was associated with elevated risks of esophageal, colorectal, laryngeal, and breast cancers. Heavy drinking was also found to contribute to the risk of stomach, liver, pancreas, and prostate cancers, thereby increasing the risk of almost all types of cancer. Additionally, females generally had lower cancer risks compared to males.
conclusionsOur findings highlight that cancer risks extend beyond heavy alcohol consumption to include light alcohol consumption as well. These findings suggest that there is no safe level of alcohol consumption associated with cancer risk. Our results underscore the importance of public health interventions addressing alcohol consumption to mitigate cancer risks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.