Evidence map›Paper›PMID 37905238›Full record

ReviewFrontiers in public health2023

Transforming global approaches to chronic disease prevention and management across the lifespan: integrating genomics, behavior change, and digital health solutions.

Shane A Thomas, Colette J Browning, Fadi J Charchar, Britt Klein, Marcia G Ory, Henrietta Bowden-Jones, Samuel R Chamberlain

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

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  4. From acute care to chronic disease management: integrating physical exercise into hospital settings.International journal of qualitative studies on health and well-being · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Shane A ThomasVice Chancellor's Office, Federation University, Ballarat, VIC, Australia.
Colette J BrowningInstitute of Health and Wellbeing, Federation University, Ballarat, VIC, Australia.
Fadi J CharcharHealth Innovation and Transformation Centre (HITC), Federation University, Ballarat, VIC, Australia.
Britt KleinHealth Innovation and Transformation Centre (HITC), Federation University, Ballarat, VIC, Australia.
Marcia G OryCenter for Community Health and Aging, Texas A&M University, School of Public Health, College Station, TX, United States.
Henrietta Bowden-JonesNational Problem Gambling Clinic, London, United Kingdom.
Samuel R ChamberlainDepartment of Psychiatry, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Federation University · AUTexas A&M Health Science Center · USUniversity of Cambridge · GBUniversity of Southampton · GB

Funding

Wellcome Trust 110049
6 · The paper itself

Abstract

Chronic illnesses are a major threat to global population health through the lifespan into older age. Despite world-wide public health goals, there has been a steady increase in chronic and non-communicable diseases (e.g., cancer, cardiovascular and metabolic disorders) and strong growth in mental health disorders. In 2010, 67% of deaths worldwide were due to chronic diseases and this increased to 74% in 2019, with accelerated growth in the COVID-19 era and its aftermath. Aging and wellbeing across the lifespan are positively impacted by the presence of effective prevention and management of chronic illness that can enhance population health. This paper provides a short overview of the journey to this current situation followed by discussion of how we may better address what the World Health Organization has termed the "tsunami of chronic diseases." In this paper we advocate for the development, validation, and subsequent deployment of integrated: 1. Polygenic and multifactorial risk prediction tools to screen for those at future risk of chronic disease and those with undiagnosed chronic disease. 2. Advanced preventive, behavior change and chronic disease management to maximize population health and wellbeing. 3. Digital health systems to support greater efficiencies in population-scale health prevention and intervention programs. It is argued that each of these actions individually has an emerging evidence base. However, there has been limited research to date concerning the combined population-level health effects of their integration. We outline the conceptual framework within which we are planning and currently conducting studies to investigate the effects of their integration.

Indexed as

Mental DisordersNeoplasmsChronic DiseaseHumansLongevityPublic Healthbehavior changechronic diseasesdigital healthgenomicshealthy agingpreventionrisk prediction

Identifiers

PMID37905238
PMCPMC10613497
OpenAlexW4387614387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.