Evidence map›Paper›PMID 37905119›Full record

ArticlebioRxiv : the preprint server for biology2023

Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions.

Melissa J Mann, Chris Melendez-Suchi, Maria Sukhoplyasova, Ashley R Flory, Mary Carson Irvine, Anuradha R Iyer, Hannah Vorndran, Christopher J Guerriero, Jeffrey L Brodsky, Linda M Hendershot and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Melissa J Mann
Chris Melendez-Suchi
Maria Sukhoplyasova
Ashley R Flory
Mary Carson Irvine
Anuradha R Iyer
Hannah Vorndran
Christopher J Guerriero
Jeffrey L Brodsky
Linda M Hendershot
Teresa M BuckORCID 0000-0002-9013-9756
University of Pittsburgh · USSt. Jude Children's Research Hospital · US

Funding

Role of GRP170 in ENaC Biogenesis and Renal PhysiologyR01DK117126 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUCK, TERESA M · 2019 to 2023
$1.7M
Developing a new platform to characterize and treat disease-associated polycystin variantsR21DK137149 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GUERRIERO, CHRISTOPHER JAMES · 2023 to 2023
$199k
NIDDK NIH HHS R01 DK117126NIDDK NIH HHS R21 DK137149
6 · The paper itself

Abstract

GRP170, a product of the

Identifiers

PMID37905119
PMCPMC10614942
OpenAlexW4387808355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.