Evidence map›Paper›PMID 37905030›Full record

ArticlebioRxiv : the preprint server for biology2024

Progesterone induces meiosis through two obligate co-receptors with PLA2 activity.

Nancy Nader, Lama Assaf, Lubna Zarif, Anna Halama, Sharan Yadav, Maya Dib, Nabeel Attarwala, Qiuying Chen, Karsten Suhre, Steven S Gross and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Nancy NaderCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Lama AssafCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Lubna ZarifCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Anna HalamaDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Sharan YadavCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Maya DibCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Nabeel AttarwalaDepartment of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Qiuying ChenDepartment of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Karsten SuhreDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Steven S GrossDepartment of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Khaled MachacaCalcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar.
Cornell University · USWeill Cornell Medical College in Qatar · QA

Funding

Metabolic remodeling of skeletal muscle in mitochondrial myopathiesR01AR076029 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, QIUYING, D'AURELIO, MARILENA · 2020 to 2024
$2.7M
Pho-m6A assay: A phosphoselective method to quantify dynamics of m6A in mRNAR21ES032347 · NIEHS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHEN, QIUYING, JAFFREY, SAMIE R · 2020 to 2021
$466k
NIAMS NIH HHS R01 AR076029NIEHS NIH HHS R21 ES032347
6 · The paper itself

Abstract

The steroid hormone progesterone (P4) regulates multiple aspects of reproductive and metabolic physiology. Classical P4 signaling operates through nuclear receptors that regulate transcription. In addition, P4 signals through membrane P4 receptors (mPRs) in a rapid nongenomic modality. Despite the established physiological importance of P4 nongenomic signaling, the details of its signal transduction cascade remain elusive. Here, using

Indexed as

ABHD2lipidomicsmeiosismembrane progesterone receptor β (mPRβ)metabolomicsnongenomicoocyte maturationPhospholipase A2progesterone signalingXenopus laevis

Identifiers

PMID37905030
PMCPMC10614741
OpenAlexW4386588747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.