Evidence map›Paper›PMID 37904930›Full record

ArticlebioRxiv : the preprint server for biology2023

High-throughput single-cell sorting by stimulated Raman-activated cell ejection.

Jing Zhang, Haonan Lin, Jiabao Xu, Meng Zhang, Xiaowei Ge, Chi Zhang, Wei E Huang, Ji-Xin Cheng

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jing ZhangDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Haonan LinDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Jiabao XuDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Glasgow, G12 8LT, UK.
Meng ZhangPhotonics Center, Boston University, Boston, MA 02215, USA.
Xiaowei GePhotonics Center, Boston University, Boston, MA 02215, USA.
Chi ZhangDepartment of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN 47907, USA.
Wei E HuangDepartment of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK.
Ji-Xin ChengDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Boston University · USPurdue University West Lafayette · USUniversity of Glasgow · GBUniversity of Oxford · GB

Funding

Vibrational Spectroscopic Imaging to Unveil Hidden Signatures in Living SystemsR35GM136223 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CHENG, JI-XIN · 2020 to 2025
$5.7M
NIGMS NIH HHS R35 GM136223
6 · The paper itself

Abstract

Single-cell sorting is essential to explore cellular heterogeneity in biology and medicine. Recently developed Raman-activated cell sorting (RACS) circumvents the limitations of fluorescence-activated cell sorting, such as the cytotoxicity of labels. However, the sorting throughputs of all forms of RACS are limited by the intrinsically small cross-section of spontaneous Raman scattering. Here, we report a stimulated Raman-activated cell ejection (S-RACE) platform that enables high-throughput single-cell sorting based on high-resolution multi-channel stimulated Raman chemical imaging,

Indexed as

Biological SciencesBiophysics and Computational Biologycell ejectioncell sortinghigh-throughput analysislaser-induced forward transferRaman spectroscopysingle microorganism isolation and culture

Identifiers

PMID37904930
PMCPMC10614813
OpenAlexW4387766666

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.