Evidence map›Paper›PMID 37904927›Full record

ArticlebioRxiv : the preprint server for biology2023

Bioinformatics Illustrations Decoded by ChatGPT: The Good, The Bad, and The Ugly.

Jinge Wang, Qing Ye, Li Liu, Nancy Lan Guo, Gangqing Hu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinge WangDepartment of Microbiology, Immunology & Cell Biology, West Virginia University, Morgantown, WV 26506, USA.
Qing YeWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Li LiuCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.
Nancy Lan GuoWest Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Gangqing HuDepartment of Microbiology, Immunology & Cell Biology, West Virginia University, Morgantown, WV 26506, USA.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI GARY O RANKIN · 2012 to 2026
$81.0M
WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI GARY O RANKIN · 2012 to 2026
$61.1M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Karen H Martin · 2018 to 2026
$22.4M
Discover and Analyze Germline-Somatic Interactions in CancerR01LM013438 · NLM · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LIU, LI, YANG, PING · 2021 to 2023
$1.0M
NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P20 GM121322NIGMS NIH HHS U54 GM104942NLM NIH HHS R01 LM013438
6 · The paper itself

Abstract

Emerging studies underscore the promising capabilities of large language model-based chatbots in conducting fundamental bioinformatics data analyses. The recent feature of accepting image-inputs by ChatGPT motivated us to explore its efficacy in deciphering bioinformatics illustrations. Our evaluation with examples in cancer research, including sequencing data analysis, multimodal network-based drug repositioning, and tumor clonal evolution, revealed that ChatGPT can proficiently explain different plot types and apply biological knowledge to enrich interpretations. However, it struggled to provide accurate interpretations when quantitative analysis of visual elements was involved. Furthermore, while the chatbot can draft figure legends and summarize findings from the figures, stringent proofreading is imperative to ensure the accuracy and reliability of the content.

Identifiers

PMID37904927
PMCPMC10614796

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.