Evidence map›Paper›PMID 37904593›Full record

ArticleNucleic acids research2024

UTexas Aptamer Database: the collection and long-term preservation of aptamer sequence information.

Ali Askari, Sumedha Kota, Hailey Ferrell, Shriya Swamy, Kayla S Goodman, Christine C Okoro, Isaiah C Spruell Crenshaw, Daniela K Hernandez, Taylor E Oliphant, Akshata A Badrayani and 2 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Super-Resolved Protein Imaging Using Bifunctional Light-Up Aptamers.Angewandte Chemie (International ed. in English) · 2024
    Article
  9. Article
  10. Article
  11. Aptamers' Potential to Fill Therapeutic and Diagnostic Gaps.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Aptamers: precision tools for diagnosing and treating infectious diseases.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ali AskariFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0003-0524-4661
Sumedha KotaFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0004-3329-7733
Hailey FerrellFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0007-2893-1260
Shriya SwamyFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0007-7787-4637
Kayla S GoodmanFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0002-6455-1090
Christine C OkoroFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0000-0003-4617-9379
Isaiah C Spruell CrenshawFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0005-3464-5530
Daniela K HernandezFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0002-7569-0467
Taylor E OliphantFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0008-4704-1455
Akshata A BadrayaniFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0009-0006-9651-1156
Andrew D EllingtonInstitute for Molecular Biosciences, The University of Texas, Austin, TX 78712, USA.ORCID 0000-0001-6246-5338
Gwendolyn M StovallFreshman Research Initiative, The University of Texas, Austin, TX 78712, USA.ORCID 0000-0002-7525-9733

Funding

Howard Hughes Medical Institute 52008124
6 · The paper itself

Abstract

A growing interest in aptamer research, as evidenced by the increase in aptamer publications over the years, has led to calls for a go-to site for aptamer information. A comprehensive, publicly available aptamer dataset, which may be a repository for aptamer data, standardize aptamer reporting, and generate opportunities to expand current research in the field, could meet such a demand. There have been several attempts to create aptamer databases; however, most have been abandoned or removed entirely from public view. Inspired by previous efforts, we have published the UTexas Aptamer Database, https://sites.utexas.edu/aptamerdatabase, which includes a publicly available aptamer dataset and a searchable database containing a subset of all aptamer data collected to date (1990-2022). The dataset contains aptamer sequences, binding and selection information. The information is regularly reviewed internally to ensure accuracy and consistency across all entries. To support the continued curation and review of aptamer sequence information, we have implemented sustaining mechanisms, including researcher training protocols, an aptamer submission form, data stored separately from the database platform, and a growing team of researchers committed to updating the database. Currently, the UTexas Aptamer Database is the largest in terms of the number of aptamer sequences with 1,443 internally reviewed aptamer records.

Indexed as

Aptamers, NucleotideDatabases, Nucleic AcidDatasets as TopicAptamers, Nucleotide

Identifiers

PMID37904593
PMCPMC10767891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.