Evidence map›Paper›PMID 37904557›Full record

ReviewRecent patents on nanotechnology2024

An Overview of Current Progress and Challenges in Brain Cancer Therapy Using Advanced Nanoparticles.

Mahima Chauhan, Rahul Pratap Singh, Sonali, Ghazala Zia, Saurabh Shekhar, Bhavna Yadav, Vandana Garg, Rohit Dutt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Recent patents on nanotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahima ChauhanDepartment of Pharmacy, School of Medical & Allied Sciences, GD Goenka University, Gurugram, 122103, India.ORCID 0000-0003-2355-5511
Rahul Pratap SinghDepartment of Pharmacy, School of Medical & Allied Sciences, GD Goenka University, Gurugram, 122103, India.ORCID 0000-0001-6807-0484
SonaliGuru Teg Bahadur Hospital, GTB Enclave, Dilshad Garden, New Delhi, Delhi, 110095, India.ORCID 0000-0002-0111-7257
Ghazala ZiaDepartment of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001, India.
Saurabh ShekharDepartment of Pharmacy, School of Medical & Allied Sciences, GD Goenka University, Gurugram, 122103, India.
Bhavna YadavDepartment of Pharmacy, School of Medical & Allied Sciences, GD Goenka University, Gurugram, 122103, India.
Vandana GargGuru Teg Bahadur Hospital, GTB Enclave, Dilshad Garden, New Delhi, Delhi, 110095, India.
Rohit DuttDepartment of Pharmacy, School of Medical & Allied Sciences, GD Goenka University, Gurugram, 122103, India.

Funding

Science and Engineering Research Board (SERB), Department of Science and Technology (DST), Ministry of Science and Technology, Government of India EEQ/2019/000218
6 · The paper itself

Abstract

Brain tumors pose significant challenges in terms of complete cure and early-stage prognosis. The complexity of brain tumors, including their location, infiltrative nature, and intricate tumor microenvironment (TME), contributes to the difficulties in achieving a complete cure. The primary objective of brain cancer therapy is to effectively treat brain tumors and improve the patient's quality of life. Nanoparticles (NPs) have emerged as promising tools in this regard. They can be designed to deliver therapeutic drugs to the brain tumor site while also incorporating imaging agents. The NPs with the 10-200 nm range can cross the blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB) and facilitate drug bioavailability. NPs can be designed by several methods to improve the pharmaceutical and pharmacological aspects of encapsulated therapeutic agents. NPs can be developed in various dosage forms to suit different administration routes in brain cancer therapy. The unique properties and versatility of NPs make them essential tools in the fight against brain tumors, offering new opportunities to improve patient outcomes and care. Having the ability to target brain tumors directly, overcome the BBB, and minimize systemic side effects makes NPs valuable tools in improving patient outcomes and care. The review highlights the challenges associated with brain tumor treatment and emphasizes the importance of early detection and diagnosis. The use of NPs for drug delivery and imaging in brain tumors is a promising approach to improving patient outcomes and quality of life. The versatility and unique properties of NPs make them valuable tools in the fight against brain tumors, and innovative NP-related patents have the potential to revolutionize healthcare.

Indexed as

Blood-Brain BarrierBrain NeoplasmsNanoparticlesAnimalsAntineoplastic AgentsDrug Delivery SystemsHumansPatents as TopicTumor MicroenvironmentAntineoplastic AgentsBlood-brain barrierbrain tumor inhibitionchemotherapyclinical translation of nanomedicinesnanoparticles.theranostic approaches

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.