Evidence map›Paper›PMID 37904541›Full record

ArticleNeuro-oncology2024

Emotion recognition in relation to tumor characteristics in patients with low-grade glioma.

Femke F Siebenga, Hiska L van der Weide, Floor Gelmers, Sandra E Rakers, Miranda C A Kramer, Anouk van der Hoorn, Roelien H Enting, Ingeborg Bosma, Rob J M Groen, Hanne-Rinck Jeltema and 3 more

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Article in Neuro-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Femke F SiebengaDepartment of Neurology, Unit of Neuropsychology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Hiska L van der WeideDepartment of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Floor GelmersDepartment of Neurology, Unit of Neuropsychology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Sandra E RakersDepartment of Neurology, Unit of Neuropsychology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Miranda C A KramerDepartment of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Anouk van der HoornDepartment of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Roelien H EntingDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Ingeborg BosmaDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Rob J M GroenDepartment of Neurosurgery, University Medical Center Groningen, University of Groningen.
Hanne-Rinck JeltemaDepartment of Neurosurgery, University Medical Center Groningen, University of Groningen.
Michiel WagemakersDepartment of Neurosurgery, University Medical Center Groningen, University of Groningen.
Jacoba M SpikmanDepartment of Neurology, Unit of Neuropsychology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Anne M BuunkDepartment of Neurology, Unit of Neuropsychology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with low-grade gliomas (LGG) treated with surgery, generally function well and have a favorable prognosis. However, LGG can affect neurocognitive functioning. To date, little is known about social cognition (SC) in these patients, although impaired SC is related to social-behavioral problems and poor societal participation. Frontal brain areas are important for SC and LGG frequently have a frontal location. Therefore, the aim of the present study was to investigate whether emotion recognition, a key component of SC, was impaired, and related to general cognition, tumor location, laterality, tumor volume, and histopathological characteristics in patients with LGG, postsurgery, and before start of adjuvant therapy.

methodsA total of 121 patients with LGG were matched with 169 healthy controls (HC). Tumor location [including (frontal) subregions; insula, anterior cingulate cortex, lateral prefrontal cortex (LPFC), orbitofrontal-ventromedial PFC] and tumor volume were determined on MRI scans. Emotion recognition was measured with the Ekman 60 faces test of the Facial Expressions of Emotion-Stimuli and Tests (FEEST).

resultsPatients with LGG performed significantly lower on the FEEST than HC, with 33.1% showing impairment compared to norm data. Emotion recognition was not significantly correlated to frontal tumor location, laterality, and histopathological characteristics, and significantly but weakly with general cognition and tumor volume.

conclusionsEmotion recognition is impaired in patients with LGG but not (strongly) related to specific tumor characteristics or general cognition. Hence, measuring SC with individual neuropsychological assessment of these patients is crucial, irrespective of tumor characteristics, to inform clinicians about possible impairments, and consequently offer appropriate care.

Indexed as

Cognitive DysfunctionGliomaCognitionEmotionsFacial ExpressionHumansNeuropsychological TestsRecognition, Psychologyemotion recognitionfrontal tumor location | low-grade gliomatumor volume

Identifiers

PMID37904541
PMCPMC10912004

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