ArticleBMC geriatrics2023
Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Triglyceride-glucose index and health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies.Cardiovascular diabetology · 2024Pooled it
- Blood-based biomarkers and delirium in critically ill adults in the ICU: a systematic review.Intensive care medicine experimental · 2026Review
- Association of triglyceride-glucose index (TyG) and a body shape index (ABSI) with cognitive decline and dementia risk.PloS one · 2026Article
- Research advances on acute kidney injury and brain dysfunction.Frontiers in nephrology · 2026Review
- Association of the triglyceride-glucose index with the severity and short-term prognosis of Guillain-Barré syndrome.Frontiers in immunology · 2026Article
- Development and validation of the C-reactive protein-triglyceride-glucose index for predicting short- and long-term mortality in critically ill patients with coronary artery disease: a multicenter cohort study.Frontiers in cardiovascular medicine · 2026Article
- Triglyceride-glucose index and postoperative delirium: a retrospective study exploring a lipid-related marker in neuropsychiatric risk stratification after gastric surgery.Lipids in health and disease · 2025Article
- Association between triglyceride-glucose index and postoperative delirium following cardiac surgery: a multicenter retrospective analysis.Lipids in health and disease · 2025Article
- Frailty as an independent risk factor for sepsis-associated delirium: a cohort study of 11,740 older adult ICU patients.Aging clinical and experimental research · 2025Article
- Association between the triglyceride-glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study.Journal of intensive care · 2025Article
- Comparative analysis of four nutritional scores in predicting delirium in ICU patients.Frontiers in nutrition · 2025Article
- Triglyceride-glucose index: a novel prognostic marker for sepsis-associated encephalopathy severity and outcomes.Frontiers in neurology · 2025Article
- Associations between triglyceride-glucose indices and delirium risk in critically ill patients with acute kidney injury: a retrospective study.Frontiers in endocrinology · 2025Article
- Association between triglyceride-glucose index and the risk of heart failure hospitalization in older diabetic patients received right ventricular pacing: a retrospective cohort study.Acta diabetologica · 2024Article
- Nutritional status and triglyceride-glucose index influence delirium in elderly heart failure patients.Scientific reports · 2024Article
- Predictive value of the triglyceride-glucose index for short- and long-term all-cause mortality in patients with critical coronary artery disease: a cohort study from the MIMIC-IV database.Lipids in health and disease · 2024Article
- Association of triglyceride-glucose index and delirium in patients with sepsis: a retrospective study.Lipids in health and disease · 2024Article
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8 authors.
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Abstract
backgroundThe triglyceride-glucose index (TyG), an established indicator of insulin resistance, is closely correlated with the prognosis of several metabolic disorders. This study aims to investigate the association between the TyG index and the incidence of critical delirium in patients aged 65 years and older.
methodsWe focused on evaluating patients aged 65 years and older diagnosed with critical delirium. Data were obtained from the Medical Information Database for Intensive Care (MIMIC-IV) and the eICU Collaborative Research Database (eICU-CRD). Multivariate logistic regression and restricted cubic spline (RCS) regression were used to determine the relationship between the TyG index and the risk of delirium.
resultsParticipants aged 65 years and older were identified from the MIMIC-IV (n = 4,649) and eICU-CRD (n = 1,844) databases. Based on optimal thresholds derived from RCS regression, participants were divided into two cohorts: Q1 (< 8.912), Q2 (≥ 8.912). The logistic regression analysis showed a direct correlation between the TyG index and an increased risk of critical delirium among ICU patients aged 65 and older. These findings were validated in the eICU-CRD dataset, and sensitivity analysis further strengthened our conclusions. In addition, the subgroup analysis revealed certain differences.
conclusionThis study highlights a clear, independent relationship between the TyG index and the risk of critical delirium in individuals aged 65 years and older, suggesting the importance of the TyG index as a reliable cardio-cerebrovascular metabolic marker for risk assessment and intervention.
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