Evidence map›Paper›PMID 37904024›Full record

ArticleHNO2023

Bilateral intracochlear schwannomas: histopathological confirmation and outcomes following tumour removal and cochlear implantation with lateral wall electrodes.

Mark E Quick, Shannon Withers, Stefan K Plontke, Ronel Chester-Browne, Jafri Kuthubutheen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HNO, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Cochlear implantation in patients with inner ear schwannomas: a systematic review and meta-analysis of audiological outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mark E QuickDepartment of Otolaryngology, Sir Charles Gairdner Hospital, Hospital Avenue, 6009, Nedlands, Perth, Western Australia, Australia. mark.quick@health.wa.gov.au.
Shannon WithersDepartment of Otolaryngology, Sir Charles Gairdner Hospital, Hospital Avenue, 6009, Nedlands, Perth, Western Australia, Australia.
Stefan K PlontkeDepartment of Otorhinolaryngology, Head and Neck Surgery, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Ronel Chester-BrowneEar Science Implant Clinic, Perth, Western Australia, Australia.
Jafri KuthubutheenDepartment of Otolaryngology, Sir Charles Gairdner Hospital, Hospital Avenue, 6009, Nedlands, Perth, Western Australia, Australia.
The University of Western Australia · AUEar Science Institute Australia · AUMartin Luther University Halle-Wittenberg · DESir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracochlear schwannomas (ICS) are very rare benign tumours of the inner ear. We present histopathological proof of the extremely rare bilateral occurrence of intracochlear schwannomas with negative blood genetic testing for neurofibromatosis type 2 (NF2). Bilateral schwannomas are typically associated with the condition NF2 and this case is presumed to have either mosaicism for NF2 or sporadic development of bilateral tumours. For progressive bilateral tumour growth and associated profound hearing loss, surgical intervention via partial cochleoectomy, tumour removal, preservation of the modiolus, and simultaneous cochlear implantation with lateral wall electrode carrier with basal double electrode contacts was performed. The right side was operated on first with a 14-month gap between each side. The hearing in aided speech recognition for consonant-nucleus-consonant (CNC) phonemes in quiet improved from 57% to 83% 12 months after bilateral cochlear implantation (CI). Bilateral intracochlear schwannomas in non-NF2 patients are extremely rare but should be considered in cases of progressive bilateral hearing loss. Successful tumour removal and cochlear implantation utilizing a lateral wall electrode is possible and can achieve good hearing outcomes.

Indexed as

Cochlear ImplantationCochlear ImplantsNeurilemmomaNeurofibromatosis 2Neuroma, AcousticHumansAcoustic neuromaCochleaCochlear implantInner earIntralabyrinthine

Identifiers

PMID37904024
PMCPMC10663204
OpenAlexW4388019982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.