Evidence map›Paper›PMID 37904011›Full record

ReviewMolecular biology reports2023

Gingival mesenchymal stem cell therapy, immune cells, and immunoinflammatory application.

Amir Ebrahimpour Tolouei, Farshid Oruji, Sahar Tehrani, Sara Rezaei, Asieh Mozaffari, Mohammad Jahri, Kamyar Nasiri

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

Amir Ebrahimpour ToloueiImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farshid OrujiCollege of Medicine, Department of Genetics Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA.
Sahar TehraniDepartment of Pediatric Dentistry, School of Dentistry, Ahvaz Jundishapour University of Medical Sciences Ahvaz, Ahvaz, Iran.
Sara RezaeiRestorative Dentistry Resident, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.
Asieh MozaffariDepartment of Periodontics, Faculty of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Mohammad JahriDental Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Dr.jahri@hotmail.com.
Kamyar NasiriDepartment of Dentistry, Islamic Azad University, Tehran, Iran. kamyar-nasiri@hotmail.com.
Ahvaz Jundishapur University of Medical Sciences · IRIslamic Azad University, Tehran · IRKerman University of Medical Sciences · IRQazvin University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRTabriz University of Medical Sciences · IRUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MSC-based therapeutic strategies have proven to be incredibly effective. Robust self-renewal, multilineage differentiation, and potential for tissue regeneration and disease treatments are all features of MSCs isolated from oral tissue. Human exfoliated deciduous teeth, dental follicles, dental pulp, apical papilla SCs, and alveolar bone are the primary sources of oral MSC production. The early immunoinflammatory response is the first stage of the healing process. Oral MSCs can interact with various cells, such as immune cells, revealing potential immunomodulatory regulators. They also have strong differentiation and regeneration potential. Therefore, a ground-breaking strategy would be to research novel immunomodulatory approaches for treating disease and tissue regeneration that depend on the immunomodulatory activities of oral MSCs during tissue regeneration.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationCell DifferentiationCells, CulturedGingivaHumansGMSCsInnate immunityMSCsSpecifi immunity

Identifiers

PMID37904011
OpenAlexW4388018099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.