ArticleNature biomedical engineering2024
A temperature-responsive intravenous needle that irreversibly softens on insertion.
Article in Nature biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- A terminator-inspired liquid metal stent for treating atherosclerotic vascular stenosis with precise vascular matching and magnetothermally regulated active degradation.Materials today. Bio · 2026Article
- Chemical-Sensing Catheters for Long-Term and Personalized Therapeutic Management.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Liquid Metals for Reconfigurable Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Electronics with switchable flexibility for 3D conforming neural interfaces.Science advances · 2026Article
- Multi-Functional Adaptive Interfaces for Next-Generation Wearable and Implantable Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- NIR-switched DNA tweezer enables reversible miRNA recognition with erasable signal for in vivo continuous imaging.Science advances · 2026Article
- Cell-Stress-Free Percutaneous Bioelectrodes.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Magnetically controlled microrobotic system for programmable stiffness tuning and active steering of microcatheters.Nature communications · 2025Article
- Damage-tolerant stretchable ionic conductors.Fundamental research · 2025Review
- Phase-change metal ink with pH-controlled chemical sintering for versatile and scalable fabrication of variable stiffness electronics.Science advances · 2025Article
- Tough hydrogel-coated containment capsule of magnetic liquid metal for remote gastrointestinal operation.National science review · 2025Article
- High-entropy thermal-stiffening hydrogels with fast switching dynamics.National science review · 2025Article
- A Smart Semi-Implantable Device Integrating Microchannel-Enhanced Sampling and Multiplex Biochemical Testing for Deep Wound Monitoring and Pathogen Identification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Towards device technologies non-invasive to our daily lives.Nature communications · 2025Article
- Review of Liquid Metal Fiber Based Biosensors and Bioelectronics.Biosensors · 2024Review
- A needle that softens on intravenous insertion.Nature biomedical engineering · 2024Article
- Body-temperature softening electronic ink for additive manufacturing of transformative bioelectronics via direct writing.Science advances · 2024Article
- One-Dimensional Implantable Sensors for Accurately Monitoring Physiological and Biochemical Signals.Research (Washington, D.C.) · 2024Review
- A study on the fabrication of metal microneedle array electrodes for ECG detection based on low melting point Bi-In-Sn alloys.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
The high stiffness of intravenous needles can cause tissue injury and increase the risk of transmission of blood-borne pathogens through accidental needlesticks. Here we describe the development and performance of an intravenous needle whose stiffness and shape depend on body temperature. The needle is sufficiently stiff for insertion into soft tissue yet becomes irreversibly flexible after insertion, adapting to the shape of the blood vessel and reducing the risk of needlestick injury on removal, as we show in vein phantoms and ex vivo porcine tissue. In mice, the needles had similar fluid-delivery performance and caused substantially less inflammation than commercial devices for intravenous access of similar size. We also show that an intravenous needle integrated with a thin-film temperature sensor can monitor core body temperature in mice and detect fluid leakage in porcine tissue ex vivo. Temperature-responsive intravenous needles may improve patient care.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.